Trial of antihypertensive interventions and management. Design, methods, and selected baseline results.
B R Davis, M D Blaufox, C M Hawkins...
https://pubmed.ncbi.nlm.nih.gov/2649308Completed
Phase 3
Age: 21Years - 65Years
All Genders
ID00000513
Led by National Heart, Lung, and Blood Institute (NHLBI) · Updated on 2013-11-26
N/A
Participants Needed
N/A
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
The objective of the Trial of Antihypertensive Intervention Management (TAIM) was to determine the efficacy of dietary management and/or drug therapy, namely thiazide-like diuretics or a beta-blocker, in the control of mild hypertension. Additionally, the Continuation of the Trial of Antihypertensive Intervention Management (COTAIM) tested the effects of long-term weight reduction, and sodium/potassium changes added to weight reduction, as well as the original drug treatment, on the failure rate of blood pressure control.
CONDITIONS
Official Title
Trial of Antihypertensive Intervention Management
Who Can Participate
Age: 21Years - 65Years
All Genders
Eligibility Criteria
You may qualify if you...
Men and women, ages 21 to 65, with mild hypertension in the range of 90 to 100 mm Hg diastolic blood pressure.
Subjects were obese (110-150 percent of ideal weight).
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Trial Site Locations
Site Locations not provided
Location information for this trial is currently unavailable.
How is the study designed?
Study Type
INTERVENTIONAL
Masking
N/A
Allocation
RANDOMIZED
Model
N/A
Primary Purpose
TREATMENT
Number of Arms
0
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Published Research Related To This Trial
Effect of weight loss on thiazide produced erectile problems in men.
H G Langford, R W Rockhold, S Wassertheil-Smoller...
https://pubmed.ncbi.nlm.nih.gov/2486442Pharmacologic and nutritional treatment of mild hypertension: changes in cardiovascular risk status.
A Oberman, S Wassertheil-Smoller, H G Langford...
https://pubmed.ncbi.nlm.nih.gov/1967210Effect of drug and diet treatment of mild hypertension on diastolic blood pressure. The TAIM Research Group.
H G Langford, B R Davis, D Blaufox...
https://pubmed.ncbi.nlm.nih.gov/1671380Effect of antihypertensives on sexual function and quality of life: the TAIM Study.
S Wassertheil-Smoller, M D Blaufox, A Oberman...
https://pubmed.ncbi.nlm.nih.gov/2003706Sodium-potassium interaction in hypertension and hypertensive cardiovascular disease.
H G Langford
https://pubmed.ncbi.nlm.nih.gov/1986994The Trial of Antihypertensive Interventions and Management (TAIM) study. Adequate weight loss, alone and combined with drug therapy in the treatment of mild hypertension.
S Wassertheil-Smoller, M D Blaufox, A S Oberman...
https://pubmed.ncbi.nlm.nih.gov/1728908Effect of antihypertensive therapy on weight loss. The Trial of Antihypertensive Interventions and Management Research Group.
B R Davis, A Oberman, M D Blaufox...
https://pubmed.ncbi.nlm.nih.gov/1555871The Trial of Antihypertensive Interventions and Management (TAIM) Study. Final results with regard to blood pressure, cardiovascular risk, and quality of life.
S Wassertheil-Smoller, A Oberman, M D Blaufox...
https://pubmed.ncbi.nlm.nih.gov/1736933Renin predicts diastolic blood pressure response to nonpharmacologic and pharmacologic therapy.
M D Blaufox, H B Lee, B Davis...
https://pubmed.ncbi.nlm.nih.gov/1538559