Actively Recruiting
A Trial Of Approach Bias Modification Training During Treatment For Cocaine Use Disorder
Led by ASST Fatebenefratelli Sacco · Updated on 2025-12-24
60
Participants Needed
1
Research Sites
30 weeks
Total Duration
On this page
Sponsors
A
ASST Fatebenefratelli Sacco
Lead Sponsor
M
Monash University
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to investigate if the intervention "Approach Bias Modification" (ABM) can low cocaine craving in people with Cocaine Use Disorder (CUD). The main question this clinical trial aims to answer is how many days participants can be in abstinence from cocaine after 4 ABM sessions. ABM is a computerised training aiming to train the participants to: * avoid drug-related images by pushing a joystick which causes the image to disappear; * approach positive images by pulling a joystick which causes the image to expand. Researchers will compare participants treated with ABM to those who receive Treatment As Usual (TAU) condition to see if ABM training for CUD is more effective in increasing the number of abstinent days. * Participants will attend 1 ABM session per week for a total of 4 sessions, each lasting 15 minutes. * Both cocaine and non-cocaine positive images relative to the subjective values or interests (i.e. effects, sport, music, nature, work, etc.) are presented to the participant, in portrait or landscape orientation. * Participants are instructed to push the joystick if the image is portrait-oriented (cocaine-related images) or to pull the joystick if it is landscape-oriented (positive images). * At 1 and 3-month-follow up, participants will complete self-report questionnaires to measure abstinence days and describe the effect of ABM on cocaine use, dependence symptoms, and approach bias.
CONDITIONS
Official Title
A Trial Of Approach Bias Modification Training During Treatment For Cocaine Use Disorder
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants must be aged at least 18 years
- Current DSM 5 TR Cocaine Use Disorder diagnosis
- Sufficient Italian language proficiency to understand information sheet, questionnaires, and instructions
- Signed informed consent form
You will not qualify if you...
- Neurological disorder, injury, or brain trauma with loss of consciousness longer than 30 minutes
- Severe psychiatric disorder as judged clinically
- Use of antipsychotic medication
- Intellectual disability
- Missing informed consent
- Planned absence during the one-month training period
AI-Screening
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Trial Site Locations
Total: 1 location
1
Struttura Semplice Servizio Dipendenze
Milan, Milano, Italy, 20131
Actively Recruiting
Research Team
S
Stefania Cheli, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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