Actively Recruiting

Phase Not Applicable
Age: 18Years - 90Years
All Genders
NCT06743789

Trial in Arrhythmia Radioablation for Ventricular Tachycardia: Single Fraction vs Three Fractions

Led by Weill Medical College of Cornell University · Updated on 2026-01-26

40

Participants Needed

1

Research Sites

310 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a research study that aims to understand if giving a lower dose of treatment all at once is as effective and safe as dividing it into three smaller doses for patients with a heart condition called refractory ventricular tachycardia (VT). These patients have not exhibited positive responses to conventional medications or procedures. This study aims to explore whether an alternative approach could yield more beneficial outcomes.

CONDITIONS

Official Title

Trial in Arrhythmia Radioablation for Ventricular Tachycardia: Single Fraction vs Three Fractions

Who Can Participate

Age: 18Years - 90Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Diagnosed with ischemic cardiomyopathy, non-ischemic cardiomyopathy, or hypertrophic cardiomyopathy
  • Ventricular tachycardia causing ICD shock with at least 3 episodes in any 3-month period without reversible cause
  • Failed or intolerant to antiarrhythmic drug therapy (amiodarone or at least 2 other drugs) and failed catheter ablation
  • Or catheter ablation is contraindicated
  • Able to understand the study and provide informed consent
  • Willing to follow all study testing, evaluations, and requirements
  • Expected to be available for follow-up for at least 36 months after enrollment
Not Eligible

You will not qualify if you...

  • Younger than 18 years
  • Pregnant
  • Prior chest radiation therapy

AI-Screening

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Trial Site Locations

Total: 1 location

1

Weill Cornell Medicine

New York, New York, United States, 10065

Actively Recruiting

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Research Team

F

Fabiana Gregucci, M.D.

CONTACT

F

Fereshteh Talebi, M.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

6

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