Actively Recruiting

Phase 3
Age: 4Years - 9Years
FEMALE
NCT06510764

A Trial of Chinese Traditional Medicine Combining With Intradermal Acupuncture for Treating Precocious Puberty

Led by Children's Hospital of Fudan University · Updated on 2026-03-16

170

Participants Needed

2

Research Sites

145 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

A randomized controlled study will be conducted to evaluate the therapeutic effect of traditional Chinese medicine and acupoints stimulation on children with idiopathic precocious puberty.

CONDITIONS

Official Title

A Trial of Chinese Traditional Medicine Combining With Intradermal Acupuncture for Treating Precocious Puberty

Who Can Participate

Age: 4Years - 9Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Girls diagnosed with idiopathic precocious puberty with onset at or below 7.5 years old
  • Breast development at Tanner stage III or below with mammillary nucleus diameter 3 cm or less
  • Ultrasound showing uterus volume at least 3 ml, ovary volume at least 1.5 ml, follicle diameter 4 mm or less
  • Bone age less than 1 year ahead of chronological age and less than 10 years old
  • No prior treatment with GnRH analogs or sex hormones
Not Eligible

You will not qualify if you...

  • Precocious puberty caused by central nervous system organic diseases
  • Precocious puberty due to congenital hypothyroidism, adrenal diseases, tumors, or McCune-Albright syndrome
  • Family history of tumors, leukemia, diabetes, or systemic lupus erythematous
  • Pseudo sexual precocity or partial precocious puberty

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Children's Hospital of Fudan university

Shanghai, Shanghai Municipality, China, 201102

Actively Recruiting

2

Children's Hospital of Fudan University

Shanghai, China, 201102

Actively Recruiting

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Research Team

H

Han Xinghui, Master

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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