Actively Recruiting

Age: 1Year - 6Years
All Genders
NCT07066540

Trial of the Efficacy and Safety of Use of Drug Product Reamberin® for Pathogenetic Therapy of Viral Enteric Infection in Children Aged 1-6 Years Old

Led by POLYSAN Scientific & Technological Pharmaceutical Company · Updated on 2025-07-15

300

Participants Needed

8

Research Sites

121 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To assess the efficacy and safety of use of drug product Reamberin® solution for infusion, 1.5 % (Scientific Technological Pharmaceutical Firm "POLYSAN") for pathogenetic therapy of viral enteric infection in children aged 1-6 years old in routine clinical practice. Trial population: children of both sexes at the age of 1-6 years old inclusive with viral enteric infection.

CONDITIONS

Official Title

Trial of the Efficacy and Safety of Use of Drug Product Reamberin® for Pathogenetic Therapy of Viral Enteric Infection in Children Aged 1-6 Years Old

Who Can Participate

Age: 1Year - 6Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Children of both sexes aged 1 to 6 years old inclusive
  • Diagnosis of viral and other specified intestinal infections (ICD-10 code: A08)
  • Clinical signs of endogenous intoxication such as nausea, vomiting, fever, headache, muscle pain, weakness, or fatigue
  • Indication for infusion therapy (parenteral rehydration)
  • Physician's decision to prescribe Reamberin� solution for infusion, 1.5% at 10 mL/kg daily dose with appropriate fluid solutions
  • Diagnosis confirmed by laboratory tests with biological material taken
  • Signed informed consent form by a parent or legal representative
Not Eligible

You will not qualify if you...

  • Known intolerance or hypersensitivity to sodium meglumine, sodium succinate, normal saline, glucose solutions, Ringer's solution, or Reamberin� excipients
  • Contraindications to prescribing Reamberin�
  • Need for surgical intervention during the trial
  • Previous enrollment in this trial with discontinued participation for any reason
  • Use of antibiotics or succinate-containing drugs (such as Cytoflavin, Mexidol) or malate-containing solutions
  • Any other condition that prevents enrollment or may cause early trial discontinuation as judged by the investigator

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 8 locations

1

South Ural State Medical University

Chelyabinsk, Russia

Actively Recruiting

2

Khimki Clinical Hospital

Khimki, Russia

Actively Recruiting

3

Kuban State Medical University

Krasnodar, Russia

Actively Recruiting

4

Infectious Diseases Clinical Hospital No. 1

Moscow, Russia

Actively Recruiting

5

Z.A. Bashlyaeva Children's City Clinical Hospital

Moscow, Russia

Actively Recruiting

6

Penza Regional Clinical Center for Specialized Types of Medical Care

Penza, Russia

Actively Recruiting

7

Children's Scientific and Clinical Center for Infectious Diseases of the Federal Medical and Biological Agency

Saint Petersburg, Russia

Actively Recruiting

8

Samarkand State Medical University

Samarkand, Uzbekistan

Actively Recruiting

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Research Team

A

Alexey Kovalenko, Doc Biol Sci

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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