Actively Recruiting
A Trial of HRS-5041-103 to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of HRS-5041 in Subjects With Metastatic Castration-resistant Prostate Cancer
Led by Atridia Pty Ltd. · Updated on 2026-01-15
25
Participants Needed
11
Research Sites
91 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of 5041-103 in Subjects with Metastatic Castration-resistant Prostate Cancer.
CONDITIONS
Official Title
A Trial of HRS-5041-103 to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of HRS-5041 in Subjects With Metastatic Castration-resistant Prostate Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ability to understand the trial procedures and possible adverse events and voluntarily participate in the trial
- Adequate bone marrow and other vital organ functions
- Adequate liver function tests
- Diagnosis of metastatic castration-resistant prostate cancer
You will not qualify if you...
- Planning to receive any other anti-tumor therapy during the study
- Received chemotherapy, targeted therapy, immunotherapy, live/attenuated vaccination, radiotherapy, or surgery within 4 weeks prior to first dosing
- Uncontrolled hypertension (SBP > 150 mmHg and/or DBP > 100 mmHg despite treatment)
- Conditions affecting oral administration or absorption of the investigational product such as swallowing difficulties, chronic diarrhea, bowel obstruction, or active gastrointestinal disease
- Known history of drug allergies or specific allergies like asthma, urticaria, or eczema
- Active heart disease within 6 months prior to first dosing
- History of other malignant tumors within 5 years prior to dosing
- Positive tests for hepatitis B virus, hepatitis C virus, syphilis, or severe infections needing treatment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 11 locations
1
GenesisCare North Shore (Oncology)
Sydney, New South Wales, Australia
Actively Recruiting
2
Sydney Adventist Hospital
Sydney, New South Wales, Australia
Actively Recruiting
3
Cancer Research SA
Adelaide, South Australia, Australia
Actively Recruiting
4
Southern Oncology Clinical Research Unit
Adelaide, South Australia, Australia
Actively Recruiting
5
Icon Cancer Centre South Brisbane
Brisbane, Australia
Actively Recruiting
6
John Flynn Private Hospital
Brisbane, Australia
Actively Recruiting
7
Eastern Health (Box Hill Hospital)
Melbourne, Australia
Actively Recruiting
8
Linear Clinical Research Ltd
Perth, Australia
Actively Recruiting
9
Macquarie University
Sydney, Australia
Actively Recruiting
10
MUPharm Pty Limited trading as Macquarie University Hospital Pharmacy
Sydney, Australia
Actively Recruiting
11
Illawarra Shoalhaven Local Health District (Wollongong Hospital)
Wollongong, Australia
Actively Recruiting
Research Team
K
Kathy You
CONTACT
R
Ravi Patel
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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