Actively Recruiting
Trial to Investigate the Benefit of Elective Para-Aortic Radiotherapy (PART) for pN1 Prostate Cancer
Led by Universitaire Ziekenhuizen KU Leuven · Updated on 2024-07-03
137
Participants Needed
1
Research Sites
416 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Prospective non-randomized phase 2 trial to study the efficacy of additional elective para-aortic RT (PART) in pN1 patients compared to those who were historically treated with adjuvant whole pelvic radiotherapy (WPRT) alone.
CONDITIONS
Official Title
Trial to Investigate the Benefit of Elective Para-Aortic Radiotherapy (PART) for pN1 Prostate Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Signed informed consent and willingness to comply with the treatment and follow-up
- Histopathologically confirmed prostate cancer diagnosis
- No previous treatment for prostate cancer
- Presence of pN1 disease after extended pelvic lymph node dissection (criteria defined in protocol)
- Age over 18 years
- Karnofsky Performance score greater than 70
- Ability to understand and provide informed consent according to the Helsinki Declaration
You will not qualify if you...
- Recurrent prostate cancer
- Presence of metastatic disease classified as cM1a, cM1b, or cM1c
- Prior radiotherapy preventing whole pelvic or para-aortic radiotherapy
- Previous malignancy not disease-free for more than 5 years, except basal cell skin cancer
- Severe or active other illnesses likely to affect feasibility of radiotherapy
- Cognitive or other disorders preventing understanding of trial information
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
UZ Leuven
Leuven, Belgium, 3000
Actively Recruiting
Research Team
G
Gert De Meerleer, Prof. Dr.
CONTACT
C
Charlien Berghen, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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