Actively Recruiting

Phase 1
Phase 2
Age: 18Years - 75Years
All Genders
NCT06605222

A Trial of SHR-7787 Injection in Patients With Advanced Solid Tumors

Led by Shanghai Hengrui Pharmaceutical Co., Ltd. · Updated on 2024-10-18

201

Participants Needed

1

Research Sites

112 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The study is being conducted to evaluate safety, tolerability, pharmacokinetics and preliminary efficacy of SHR-7787 injection monotherapy for patients with advanced solid tumors. To explore the reasonable dosage of SHR-7787 injection monotherapy for patients with advanced solid tumors.

CONDITIONS

Official Title

A Trial of SHR-7787 Injection in Patients With Advanced Solid Tumors

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Ability to understand and voluntarily agree to participate by giving written informed consent
  • Diagnosis of unresectable recurrent or metastatic solid tumors
  • Presence of at least one measurable tumor lesion
  • Eastern Cooperative Oncology Group (ECOG) performance status score of 0 or 1
  • Adequate organ functions as defined in the protocol
  • Life expectancy of 3 months or more
Not Eligible

You will not qualify if you...

  • Known active central nervous system (CNS) metastases
  • History of another malignancy within five years before the first dose
  • Tumor-related pain that cannot be controlled
  • Serious cardiovascular or cerebrovascular diseases
  • Uncontrollable third-space effusion such as pleural, pericardial, or peritoneal effusion
  • Severe infections
  • History of immunodeficiency
  • History of autoimmune diseases
  • Unresolved toxicity greater than Grade 1 from prior anti-tumor therapy
  • Active infection
  • Pregnant or nursing women
  • Known serious allergic reactions to the investigational product or its main ingredients

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Shanghai Pulmonary Hospital

Shanghai, Shanghai Municipality, China, 200433

Actively Recruiting

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Research Team

K

Ke Ma

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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