Actively Recruiting
A Trial to Test if TEV-56286 is Effective for Treatment of Participants With Multiple System Atrophy
Led by Teva Branded Pharmaceutical Products R&D LLC · Updated on 2026-05-12
350
Participants Needed
54
Research Sites
154 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The primary objective of the study is to evaluate the efficacy of TEV-56286 administered orally for the treatment of adult participants with Multiple System Atrophy (MSA). A secondary objective of the study is to evaluate specific efficacy parameters of TEV-56286. Another secondary objective is to evaluate the safety and tolerability of TEV-56286. The planned study period per participant is 56 weeks including a screening period (up to 4 weeks), a 48-week double-blind treatment period, and a follow-up visit (approximately 4 weeks after the end of the double-blind treatment period). The study duration will be approximately 27 months.
CONDITIONS
Official Title
A Trial to Test if TEV-56286 is Effective for Treatment of Participants With Multiple System Atrophy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of clinically possible or probable Multiple System Atrophy according to Gilman criteria
- Medically and psychiatrically stable based on history and examination
- Females of childbearing potential must have a negative pregnancy test at screening and baseline
- Females of childbearing potential whose male partners are fertile must use highly effective birth control
- Males who are fertile and their female partners of childbearing potential must use highly effective birth control
You will not qualify if you...
- Two or more relatives with a history of Multiple System Atrophy suggesting another diagnosis
- Participation in another investigational medicinal product study within 3 months or 5 half-lives before screening
- History of alcohol or substance abuse in the 12 months before screening
- Female participants who are pregnant, breastfeeding, or planning pregnancy during the study
- Known allergy to any components of the investigational medicinal product
- Being part of a vulnerable population such as people detained in jail
- Use of prohibited medications within specified exclusion periods
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 54 locations
1
Teva Investigational Site 15554
La Jolla, California, United States, 92037
Active, Not Recruiting
2
Teva Investigational Site 15545
Los Angeles, California, United States, 90095
Not Yet Recruiting
3
Teva Investigational Site 15547
Washington D.C., District of Columbia, United States, 20007
Active, Not Recruiting
4
Teva Investigational Site 15544
Boca Raton, Florida, United States, 33486
Active, Not Recruiting
5
Teva Investigational Site 15555
Tampa, Florida, United States, 33613
Active, Not Recruiting
6
Teva Investigational Site 15550
Chicago, Illinois, United States, 60612-3852
Active, Not Recruiting
7
Teva Investigational Site 15546
Kansas City, Kansas, United States, 66160
Actively Recruiting
8
Teva Investigational Site 15736
Boston, Massachusetts, United States, 02115
Actively Recruiting
9
Teva Investigational Site 15870
Farmington Hills, Michigan, United States, 48334
Not Yet Recruiting
10
Teva Investigational Site 15552
Rochester, Minnesota, United States, 55905
Actively Recruiting
11
Teva Investigational Site 15549
New York, New York, United States, 10016
Actively Recruiting
12
Teva Investigational Site 15551
New York, New York, United States, 10032-3726
Actively Recruiting
13
Teva Investigational Site 15553
Durham, North Carolina, United States, 27705-4410
Actively Recruiting
14
Teva Investigational Site 15735
Hershey, Pennsylvania, United States, 17033
Not Yet Recruiting
15
Teva Investigational Site 15548
Pittsburgh, Pennsylvania, United States, 15213
Actively Recruiting
16
Teva Investigational Site 15869
Georgetown, Texas, United States, 78628
Not Yet Recruiting
17
Teva Investigational Site 15873
Alexandria, Virginia, United States, 22310
Active, Not Recruiting
18
Teva Investigational Site 15543
Spokane, Washington, United States, 99202
Active, Not Recruiting
19
Teva Investigational Site 35290
Bordeaux, France, 33400
Actively Recruiting
20
Teva Investigational Site 35289
Marseille, France, 13385
Actively Recruiting
21
Teva Investigational Site 35291
Salpêtrière, France, 75651 Paris Ced
Active, Not Recruiting
22
Teva Investigational Site 35292
Toulouse, France, 31059
Actively Recruiting
23
Teva Investigational Site 32823
Beelitz-Heilstätten, Germany, 14547
Active, Not Recruiting
24
Teva Investigational Site 32818
Dresden, Germany, 01307
Active, Not Recruiting
25
Teva Investigational Site 32822
Düsseldorf, Germany, 40225
Actively Recruiting
26
Teva Investigational Site 32825
Kassel, Germany, 34128
Actively Recruiting
27
Teva Investigational Site 32826
Leipzig, Germany, 04103
Actively Recruiting
28
Teva Investigational Site 32824
Marburg, Germany, 35033
Actively Recruiting
29
Teva Investigational Site 32820
München, Germany, 81377
Actively Recruiting
30
Teva Investigational Site 32819
Münster, Germany, 48149
Actively Recruiting
31
Teva Investigational Site 32821
Ulm, Germany, 89081
Active, Not Recruiting
32
Teva Investigational Site 80203
Haifa, Israel, 31999
Actively Recruiting
33
Teva Investigational Site 80215
Jerusalem, Israel, 9103102
Actively Recruiting
34
Teva Investigational Site 80204
Tel Aviv, Israel, 6423906
Actively Recruiting
35
Teva Investigational Site 30299
Bologna, Italy, 40139
Actively Recruiting
36
Teva Investigational Site 30297
Catania, Italy, 95123
Actively Recruiting
37
Teva Investigational Site 30298
Milan, Italy, 20132
Actively Recruiting
38
Teva Investigational Site 30294
Padova, Italy, 35127
Actively Recruiting
39
Teva Investigational Site 30296
Roma, Italy, 00163
Actively Recruiting
40
Teva Investigational Site 30295
Salerno, Italy, 84131
Active, Not Recruiting
41
Teva Investigational Site 84140
Chiba, Japan, 260-8677
Actively Recruiting
42
Teva Investigational Site 84139
Fuchū, Japan, 183-0042
Actively Recruiting
43
Teva Investigational Site 84136
Gifu, Japan, 501-1112
Actively Recruiting
44
Teva Investigational Site 84137
Niigata, Japan, 951-8520
Actively Recruiting
45
Teva Investigational Site 84138
Sagamihara, Japan, 252-0392
Active, Not Recruiting
46
Teva Investigational Site 84141
Sanda-shi, Japan, 669-1592
Actively Recruiting
47
Teva Investigational Site 84135
Sendai, Japan, 982-8555
Actively Recruiting
48
Teva Investigational Site 31323
Barcelona, Spain, 08035
Actively Recruiting
49
Teva Investigational Site 31321
Barcelona, Spain, 08036
Actively Recruiting
50
Teva Investigational Site 31324
Barcelona, Spain, 08041
Active, Not Recruiting
51
Teva Investigational Site 31327
Madrid, Spain, 28006
Actively Recruiting
52
Teva Investigational Site 31320
Pamplona, Spain, 31008
Actively Recruiting
53
Teva Investigational Site 31322
Seville, Spain, 41015
Active, Not Recruiting
54
Teva Investigational Site 31319
Valencia, Spain, 46026
Actively Recruiting
Research Team
T
Teva U.S. Medical Information
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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