Actively Recruiting

Phase 2
Age: 18Years +
All Genders
NCT06748404

TriCalm Hydrogel® in the Treatment of Immunotherapy-Related Pruritus

Led by University of California, San Diego · Updated on 2026-02-24

28

Participants Needed

1

Research Sites

200 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a phase 2, randomized, open-label, single-center study that will assess the efficacy of TriCalm Hydrogel®, a topical gel containing strontium, for treating pruritus related to immune checkpoint inhibitors (ICIs).

CONDITIONS

Official Title

TriCalm Hydrogel® in the Treatment of Immunotherapy-Related Pruritus

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 18 years or older
  • Receiving immune checkpoint inhibitors for hematologic or oncologic cancers at UC San Diego Moores Cancer Center
  • Developed grade 1-3 itching after at least one dose of immune checkpoint inhibitor
  • Allowed preexisting oral antihistamines or GABA analogs if started more than 7 days before study entry
Not Eligible

You will not qualify if you...

  • Diagnosis of primary skin disorders causing itching (e.g., atopic dermatitis, psoriasis)
  • Started any new oral or topical antipruritic medication or systemic corticosteroids within 7 days before study entry
  • Presence of open wounds on the skin
  • Itching located on the face

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of California San Diego

La Jolla, California, United States, 92037

Actively Recruiting

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Research Team

K

Karen M Yun, MD

CONTACT

L

Lung Research Team

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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