Actively Recruiting

Age: 18Years +
All Genders
NCT05837663

Trifecta-Lung cfDNA-MMDx Study

Led by University of Alberta · Updated on 2026-03-05

600

Participants Needed

18

Research Sites

213 weeks

Total Duration

On this page

Sponsors

U

University of Alberta

Lead Sponsor

N

Natera, Inc.

Collaborating Sponsor

AI-Summary

What this Trial Is About

Demonstrate the relationship between dd-cfDNA levels and HLA antibodies in blood transplant recipient and Demonstrate the Molecular Microscope® (MMDx) Diagnostic System results in indication and protocol biopsies from lung transplants.

CONDITIONS

Official Title

Trifecta-Lung cfDNA-MMDx Study

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult or older adult
Not Eligible

You will not qualify if you...

  • Declines participation or unable to give informed consent
  • Received multiple organ transplants
  • Has cancer
  • Is pregnant

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 18 locations

1

St. Joseph's Hospital and Medical Center 350 West Thomas Road, Floor 8HLT

Phoenix, Arizona, United States, 85013

Actively Recruiting

2

Division of Pulmonary, Critical Care and Sleep Medicine, University of Florida, College of Medicine

Gainesville, Florida, United States, 32610

Actively Recruiting

3

USF Health, Morsani College of Medicine, 12901 Bruce B. Downs Blvd. MDC40

Tampa, Florida, United States, 33612

Actively Recruiting

4

Indiana University Methodist Hospital 1812 N. Capitol Ave Suite W131L

Indianapolis, Indiana, United States, 46202

Actively Recruiting

5

Johns Hopkins Interventional Pulmonology, Sheikh Zayed Tower, Room 7125L, 1800 Orleans Street

Baltimore, Maryland, United States, 21287

Actively Recruiting

6

Division of Pulmonary, Allergy & Critical Care Medicine Columbia University Irving Medical Center

New York, New York, United States, 10032

Actively Recruiting

7

The Ohio State University Wexner Medical Center, 410 W 10th Ave

Columbus, Ohio, United States, 43210

Actively Recruiting

8

BAYLOR SCOTT & WHITE RESEARCH INSTITUTE , 3409 Worth Street

Dallas, Texas, United States, 75246

Actively Recruiting

9

UT Southwestern Medical Center, 5939 Harry Hines Blvd.

Dallas, Texas, United States, 75390

Actively Recruiting

10

Houston Methodist Lung Transplant Center, 6550 Fannin St., SM1001

Houston, Texas, United States, 77030

Actively Recruiting

11

UT Health San Antonio 7703 Floyd Curl Drive, MSC: 7858

San Antonio, Texas, United States, 78229

Actively Recruiting

12

The Alfred Hospital, Monash University

Melbourne, Australia

Actively Recruiting

13

Department of Thoracic Surgery, Medical University of Vienna

Vienna, Austria

Not Yet Recruiting

14

Department of Medicine, University of Alberta

Edmonton, Alberta, Canada, T6G 2G3

Actively Recruiting

15

Alberta Transplant Applied Genomics Centre, University of Alberta

Edmonton, Alberta, Canada, T^g 2E1

Actively Recruiting

16

University Health Network, Toronto General Hospital

Toronto, Ontario, Canada, M5G 2C4

Actively Recruiting

17

Motol University Hospital, V Uvalu 84

Prague, Czechia, 15006

Actively Recruiting

18

Charles University/Hospital Motol

Prague, Czechia

Actively Recruiting

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Research Team

K

Konrad S Famulski, PhD DSc

CONTACT

R

Robert Polakowski, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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