Actively Recruiting

Early Phase 1
Age: 18Years +
All Genders
Healthy Volunteers
NCT05738096

Trigeminal Evoked Responses to Improve Rhizotomy

Led by University of Minnesota · Updated on 2025-11-26

30

Participants Needed

1

Research Sites

156 weeks

Total Duration

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AI-Summary

What this Trial Is About

Trigeminal neuralgia (TGN) is a debilitating pain syndrome where electrical, shock- like jolts of pain affect the face. Trigeminal somatosensory evoked potentials (TSEPs) provide a promising modality for measuring the trigeminal sensory and nociceptive pathway by using peripheral stimulation of the trigeminal nerve (on the skin) and measuring low latency evoked potentials on the scalp (contralateral sensory cortex). While TSEPs have been measured in the past, it is not clear if implementing TSEPs into a routine neurosurgical rhizotomy procedure will be feasible. This is a prospective cohort study examining the feasibility of routinely performing TSEPs during rhizotomies for TGN.

CONDITIONS

Official Title

Trigeminal Evoked Responses to Improve Rhizotomy

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults of 18 years or older
  • Scheduled to undergo percutaneous rhizotomy for facial pain
Not Eligible

You will not qualify if you...

  • Facial pain of unclear origin or rhizotomy procedure canceled
  • For healthy controls: diagnosis or history of facial pain such as TMD or TGN
  • History of migraine
  • History of functional pain disorders such as fibromyalgia, IBS, or CRPS
  • Recent chronic pain within the last month

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Minnesota

Minneapolis, Minnesota, United States, 55455

Actively Recruiting

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Research Team

M

Matthew Maple

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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