Actively Recruiting

Phase 2
Age: 40Years +
All Genders
NCT06490081

Trilaciclib Prevents Myelosuppression With Chemoradiotherapy

Led by Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Updated on 2024-09-24

40

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To evaluate the protective effect of Trilaciclib on myelosuppression in patients with limited-stage small cell lung cancer associated with concurrent chemoradiotherapy and discuss the effect of gut microbiota changes on myelosuppression

CONDITIONS

Official Title

Trilaciclib Prevents Myelosuppression With Chemoradiotherapy

Who Can Participate

Age: 40Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Histopathology confirmed limited-stage small cell lung cancer
  • ECOG performance status score between 0 and 2
  • Good organ function without blood transfusions or hematopoietic stimulating factors within 14 days before examination
  • Suitable for treatment with Trilaciclib combined with etoposide plus cisplatin or carboplatin
  • Able to understand and sign informed consent
Not Eligible

You will not qualify if you...

  • Brain metastases with symptoms requiring local radiotherapy or hormone therapy
  • Active infections requiring systemic treatment
  • Active, known, or suspected autoimmune disease or history of autoimmune disease
  • Presence of other tumors
  • Current or past clinically significant unstable medical conditions that may affect safety or study results

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Cancer Hospital Chinese Academy of Medical Sciences

Beijing, Beijing Municipality, China, 100021

Actively Recruiting

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Research Team

X

Xinrong Lian

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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