Actively Recruiting
Triple Therapy Convenience by the Use of One or Multiple Inhalers and Digital Support in Chronic Obstructive Pulmonary Disease
Led by Franciscus Gasthuis · Updated on 2025-08-21
300
Participants Needed
1
Research Sites
207 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
TRICOLON is an investigator initiated, prospective, interventional, open-label, randomized, real-world, multi-centre, 3-arms study in the Netherlands. The primary objective is to investigate in COPD patients if single-inhaler triple therapy (SITT) is superior to multi-inhaler triple therapy (MITT) in terms of adherence to inhaled corticosteroids (ICS) therapy and to investigate if SITT with e-health support is superior to MITT and SITT without e-health support.
CONDITIONS
Official Title
Triple Therapy Convenience by the Use of One or Multiple Inhalers and Digital Support in Chronic Obstructive Pulmonary Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Clinical diagnosis of COPD for at least 1 year before the screening visit
- Age 40 years and older
- Indication for triple therapy as determined by treating physician according to GOLD guideline 2021
- Owner of mobile device compatible with e-device app with internet access (Android or iOS)
- Willing to provide written informed consent
- Current or ex-smoker
You will not qualify if you...
- Inability to comply with study procedures or treatment
- Insufficient Dutch language skills to read and understand the app (family help allowed)
- Asthma as predominant disease according to investigator; past history of asthma allowed
- Use of e-health application for COPD in past six months
- Use of any therapy interfering with study drugs per investigator
- Use of nebulized bronchodilators, e.g., via pari boy
- Pregnant or lactating women and women capable of becoming pregnant without highly effective contraception
- Mentally or legally incapacitated patients or those under official/judicial accommodation
- Inability to complete questionnaires
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Franciscus Gasthuis & Vlietland
Rotterdam, South Holland, Netherlands, 3045PM
Actively Recruiting
Research Team
L
Liz Cuperus
CONTACT
H
Hans in 't Veen
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
3
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