Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06310330

TRUST-ACE - Anticancer-treatment Cardiotoxicity Identification by Echocardiography

Led by Norwegian University of Science and Technology · Updated on 2025-06-06

250

Participants Needed

1

Research Sites

146 weeks

Total Duration

On this page

Sponsors

N

Norwegian University of Science and Technology

Lead Sponsor

S

St. Olavs Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

TRUST-ACE will compare a simplified echocardiographic protocol focusing on ventricular function with the guideline recommended comprehensive echocardiographic examination using a randomised design in follow-up of breast-cancer patients with respect to identification of cancer treatment related cardiac dysfunction (CTRCD). Secondly, the study will evaluate whether novel tools used to improve standardization of recordings as well as automated measurements of central measurements, e.g. ejection fraction (EF) and global longitudinal strain (GLS) can improve the precision of echocardiography in daily clinical practice.

CONDITIONS

Official Title

TRUST-ACE - Anticancer-treatment Cardiotoxicity Identification by Echocardiography

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Breast cancer and referral for follow-up to identify potential CTRCD
Not Eligible

You will not qualify if you...

  • Not willing or able to consent

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Trial Site Locations

Total: 1 location

1

St. Olavs hospital

Trondheim, Norway, 7491

Actively Recruiting

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Research Team

E

Espen Holte, MD. PhD

CONTACT

H

Havard Dalen, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

DIAGNOSTIC

Number of Arms

2

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