Comparing Tubeless Percutaneous Nephrolithotomy With and Without Reverse Ureteral Catheter Insertion for Treating Urinary Stones

What this Trial Is About

Researchers are studying a surgical method called tubeless percutaneous nephrolithotomy PCNL used to treat upper urinary stones. This trial compares the safety and effectiveness of tubeless PCNL performed without reverse insertion of a ureteral catheter to the traditional method that includes this catheter insertion. The study aims to explore if avoiding the catheter can reduce surgical complications related to the ureter, building on evidence that tubeless PCNL can reduce discomfort, hospital stay, and costs. Participants are randomly assigned to one of two groups an experimental group receiving tubeless PCNL without reverse ureteral catheter insertion and a control group receiving the traditional tubeless PCNL with catheter insertion. The procedure is performed by doctors at a single center over an anticipated two-year period. Both groups undergo surgery after informed consent is obtained, followed by one month of post-surgery observation. During the study, participants will have their inflammatory markers, renal bleeding, kidney function, and pain levels assessed three hours after surgery. Additional checks for complications like pneumothorax, hydrothorax, and ureteral stone street occur two days after surgery. Secondary outcomes include operation duration, length of hospital stay, hospital costs, and stone-free rates after two days. Clinical data collected throughout will be analyzed to compare the two surgical approaches.

Tubeless Percutaneous Nephrolithotomy Without Reverse Insertion of a Ureteral Catheter