Actively Recruiting
Tumor Cell and DNA Detection in the Blood, Urine and Bone Marrow of Patients With Solid Cancers
Led by University of Missouri-Columbia · Updated on 2026-05-01
620
Participants Needed
1
Research Sites
595 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Patients with resectable solid primary cancers and even limited number of metastases are potentially curable. However, most patients develop recurrences despite surgery. Circulating and disseminated tumor cell (CTC/DTC) and circulating cell-free (cf) DNA isolation from the blood, urine and bone marrow will increase understanding of cancer spread and advance knowledge to develop individualized therapies.
CONDITIONS
Official Title
Tumor Cell and DNA Detection in the Blood, Urine and Bone Marrow of Patients With Solid Cancers
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Subjects older than 18 years
- Subjects of all genders and ethnicities
- Diagnosis of a solid cancer including lung, esophageal, stomach, bile duct/pancreas, colorectal, melanoma, or sarcoma
- Patients undergoing surgery with pathologically proven or highly suspected cancer
- Patients capable of giving informed consent
- Control group includes patients without cancer history undergoing surgery for benign reasons
You will not qualify if you...
- Pregnant women
- Active secondary cancer besides basal cell skin cancer with disease burden or ongoing chemotherapy
- Hemoglobin less than 8 g/dl on the morning of procedure
- Patients needing more than 4 units of red blood cell transfusions during surgery
- Patients with bleeding disorders requiring coagulation treatment preventing bone marrow aspiration
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Ellis Fischel Cancer Center, University of Missouri
Columbia, Missouri, United States, 65212
Actively Recruiting
Research Team
J
Jussuf T Kaifi, MD, PhD
CONTACT
B
Blanche Lasta, RN
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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