Actively Recruiting

Age: 18Years +
All Genders
NCT06606028

Tumor-Informed ctDNA Testing for MRD Following Treatment of Squamous Cell Carcinoma

Led by University of California, San Francisco · Updated on 2025-12-12

250

Participants Needed

1

Research Sites

272 weeks

Total Duration

On this page

Sponsors

U

University of California, San Francisco

Lead Sponsor

H

Haystack Oncology, Inc.

Collaborating Sponsor

AI-Summary

What this Trial Is About

This is a single-center, non-interventional, observational study that evaluates the correlation of circulating tumor DNA (ctDNA) testing to cancer relapse for participants with squamous cell carcinomas (HNC) of the head and neck mucosa and skin after curative-intent primary radiation or surgery.

CONDITIONS

Official Title

Tumor-Informed ctDNA Testing for MRD Following Treatment of Squamous Cell Carcinoma

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants must have confirmed squamous cell carcinoma of the head and neck mucosa or skin.
  • Participants must be 18 years of age or older.
  • Participants must be planning to receive curative-intent surgery or radiation treatment as part of standard care.
  • Participants must be able to understand and willing to sign a written informed consent form.
Not Eligible

You will not qualify if you...

  • Participants with any contraindication to giving 20 mL of blood at each time point (up to 300 mL total over 15 collections) are excluded.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of California, San Francisco

San Francisco, California, United States, 94143

Actively Recruiting

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Research Team

S

Sonia Contreras Martinez

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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