Actively Recruiting
Tumor Microenvironment in Ovarian Cancer
Led by University of Udine · Updated on 2024-02-22
50
Participants Needed
1
Research Sites
156 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
A detailed understanding of molecular mechanism of cancer genesis is fundamental to develop innovative and personalized therapies. The new frontier in biomedical research is represented by organoids, a three-dimensional cell culture system obtained from a tissue fragment that accurately reproduces the essential properties of the original tissue in vitro, which could provide a valuable model for explanation of ovarian cancers pathogenesis and will allow to predict the response to a specific therapy. With this research project, we expect to generate ovarian cancer organoids to characterize in vitro interactions and molecular pathway among tumor cells, immune cells, and resident microbiota (intratumoral bacteria and/or microbial-derived molecules).
CONDITIONS
Official Title
Tumor Microenvironment in Ovarian Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age > 18 years
- Age < 80 years
- Serous ovarian carcinoma
- FIGO Stage III-IV
You will not qualify if you...
- Ongoing or suspended immunosuppressive therapy within the last 6 months
- Congenital or acquired immunodeficiency
- Immunosuppressive state
- Administration of chemotherapy for another neoplasm in the past 12 months
- Non-epithelial ovarian tumors
- Patients not undergoing surgical intervention
- BMI > 30
- Absence of Informed Consent
AI-Screening
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Trial Site Locations
Total: 1 location
1
Università degli Studi di Udine
Udine, UD, Italy, 33100
Actively Recruiting
Research Team
G
Giuseppe Vizzielli, Prof.
CONTACT
A
Arcieri Martina, Dott.ssa
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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