Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT04300062

Tumor Rebiopsy During Progression Under Immunotherapy for Patients With Lung Cancer

Led by Assistance Publique - Hôpitaux de Paris · Updated on 2025-09-03

50

Participants Needed

1

Research Sites

362 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The objective of the study aims to collect tumor tissue at the moment of progression under Immune checkpoint inhibitors (ICI) in biological resources center in Ambroise Paré hospital, in order to insure later study on molecular mechanism involving the progression of NSCLC and SCLC under ICI. The further analysis of research will be performed in the EA 4340 unity, Biomarkers and Clinical Trials in cancerology and onco-hematology, UVSQ, University of Paris-Saclay.

CONDITIONS

Official Title

Tumor Rebiopsy During Progression Under Immunotherapy for Patients With Lung Cancer

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with non-small cell lung cancer (NSCLC) or small cell lung cancer (SCLC)
  • Previously treated with immune checkpoint inhibitors (ICI) and experienced progression during ICI treatment
  • Provided written informed consent for the study
  • 18 years of age or older on the day of signing informed consent
Not Eligible

You will not qualify if you...

  • Under legal guardianship or curatorship
  • Unable to provide written informed consent for the study
  • Technical inability to perform tissue rebiopsy under local anesthesia

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Service de Pneumologie et Oncologie thoracique, Hôpital Ambroise Paré, APHP

Boulogne-Billancourt, France, 92100

Actively Recruiting

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Research Team

E

Etienne Giroux Leprieur, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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