Actively Recruiting
Tumour Cell Response to Acute Aerobic Exercise in Breast Cancer Survivors: Modulatory Effects of Exercise Type and Intensity
Led by Riga Stradins University · Updated on 2026-05-14
40
Participants Needed
1
Research Sites
130 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Cancer has emerged as a prominent cause of mortality in the 21st century, with breast cancer (BC) being the most diagnosed malignancy. Multidisciplinary cancer management has improved survival chances, but side effects and long-term consequences of treatments have significant implications for cancer survivors' health-related quality of life. Exercise is increasingly considered and used in cancer treatment and follow-up. However, studies demonstrating the biological mechanisms underlying the anticarcinogenic effects (ACE) of exercise are insufficient to justify the most appropriate physical activity for different clinical scenarios. Achieving scientific excellence in understanding the ACE of exercise in cancer management is critical to optimize treatment and enhance patients' quality of life.
CONDITIONS
Official Title
Tumour Cell Response to Acute Aerobic Exercise in Breast Cancer Survivors: Modulatory Effects of Exercise Type and Intensity
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female participants of reproductive age (premenopausal)
- Diagnosis of Stage II-III Triple-Negative Breast Cancer (TNBC) for intervention group
- Time between 3 to 9 months after completion of surgery, chemotherapy, radiation, and/or immunotherapy for intervention group
- Physician-certified physical fitness for exercise testing supported by echocardiography for intervention group
- Female participants of reproductive age (premenopausal) with no history of cancer for control group
- Control group matched by age, body constitution, and physical fitness to intervention group
You will not qualify if you...
- Pregnancy
- Autoimmune diseases such as thyroiditis, inflammatory bowel disease, or atopic dermatitis
- Endocrine disorders including metabolic syndrome or diabetes
- Cardiovascular diseases
- Diagnosis of any other oncological disease
- Any condition contraindicating physical activity such as asthma, COPD, spinal disc herniation, or severe iron deficiency anemia
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Laboratory of Sports and Nutrition Research
Riga, Dzirciema Street 16, Latvia, LV1007
Actively Recruiting
Research Team
D
Dace Reihmane, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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