Actively Recruiting

Age: 3Months - 12Months
All Genders
NCT07182474

Turkish Version of the BRIEF-Hammersmith Infant Neurological Examination (HINE)

Led by Kahramanmaras Sutcu Imam University · Updated on 2025-09-19

120

Participants Needed

1

Research Sites

62 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The American Academy of Pediatrics defines high-risk infants as those with preterm birth, special health care needs, family risk factors, and those at risk of early death. Factors such as premature birth, perinatal asphyxia, hypoxic-ischemic encephalopathy (HIE), periventricular leukomalacia (PVL), intraventricular hemorrhage (IVH), chronic lung disease, seizures, meningitis, hyperbilirubinemia, twin/triplet pregnancy, and intrauterine growth restriction are risk factors that can result in morbidity and mortality in infants. Regular neurological examinations and neuromotor tests are necessary for at-risk infants to identify developmental problems early and to initiate early intervention programs.In developing countries, regular follow-up and early rehabilitation of at-risk infants are not successfully implemented. 5,6 The lengthy test batteries and busy clinics are among the most significant reasons. Therefore, the development and dissemination of shorter, valid, and reliable tests is of great importance. The Hammersmith Neonatal Neurological Examination (HINE), one of the gold standard methods, consists of 26 items and takes 15-20 minutes to administer.Due to the number of items and the duration, it is not frequently used routinely. In response to this clinical need, the HINE short scale was developed in 2024.The aim of the study is to have a Turkish version of the Abstract-HINE test in Turkey and to study its validity and reliability in high-risk infants.

CONDITIONS

Official Title

Turkish Version of the BRIEF-Hammersmith Infant Neurological Examination (HINE)

Who Can Participate

Age: 3Months - 12Months
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Infants at high risk of cerebral palsy including those with periventricular hemorrhage, intracranial hemorrhage grade 2-4, cystic periventricular leukomalacia, stage 3 hypoxic ischemic encephalopathy, neonatal bilirubin encephalopathy, perinatal stroke, perinatal asphyxia, respiratory distress syndrome, bronchopulmonary dysplasia, and those needing long-term oxygen support
  • Infants with sepsis caused by gram-negative bacteria or necrotizing enterocolitis
  • Infants with infantile apnea or low 5-minute Apgar score of 3 or below
  • Infants diagnosed with intrauterine growth retardation or multiple births (twins, triplets)
  • Preterm infants with retinopathy of prematurity
  • Infants with prolonged severe hypoglycemia or hypocalcemia
  • Small for gestational age (below 3rd percentile) or large for gestational age (above 97th percentile) infants
  • Infants who received mechanical ventilation for more than 24 hours
  • Infants born at less than 32 weeks gestation or weighing less than 1500 grams
Not Eligible

You will not qualify if you...

  • Infants with any known orthopedic, systemic disease, or neurological diagnosis other than cerebral palsy

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Kahramanmaraş Sütçü imam University

Kahramanmaraş, Onikişubat, Turkey (Türkiye), 46100

Actively Recruiting

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Research Team

H

Hatice adıgüzel tat, Associate Proffessor

CONTACT

H

hatice Adiguzel tat, Associate Proffessor

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Turkish Version of the BRIEF-Hammersmith Infant Neurological Examination (HINE) | DecenTrialz