Actively Recruiting
TURN-IT FOG: Improving Turning and Freezing of Gait in People With PD
Led by Oregon Health and Science University · Updated on 2025-07-28
60
Participants Needed
3
Research Sites
108 weeks
Total Duration
On this page
Sponsors
O
Oregon Health and Science University
Lead Sponsor
M
Michael J. Fox Foundation for Parkinson's Research
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goals of this clinical trial are to 1) learn how two different rehabilitation interventions for PD can reduce Freezing of Gait (FOG) in people with Parkinson's disease, as assessed by patients, clinicians, and wearable sensors, and 2) to explore whether two different rehabilitation intervention can reduce FOG and improve daily life mobility in people with FOG sufficiently to justify a clinical trial. Participants will: * Be randomly assigned to one of two intervention groups (turning-focused agility exercise or strength-based exercise) * Have one-on-one training sessions three times per week for 6 weeks * Perform in-lab assessments before beginning and after completing the study intervention * Use wearable mobility sensors during daily life to measure their walking and balance
CONDITIONS
Official Title
TURN-IT FOG: Improving Turning and Freezing of Gait in People With PD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of idiopathic Parkinson's disease by a movement disorders neurologist using the United Kingdom Brain Bank criteria
- Reporting freezing of gait in the New Freezing of Gait questionnaire (N-FOGQ)
- Hoehn & Yahr stages II-IV
- Age between 50 and 80 years old
- Cognitive ability sufficient to participate in testing and exercise classes
- Willingness and ability to participate in exercise intervention three times per week for six weeks
You will not qualify if you...
- Major musculoskeletal or neurological disorders, structural brain disease, epilepsy, acute illness, or health history other than Parkinson's disease that significantly affect gait and turning
- Medical conditions or medications that prevent moderate-intensity exercise
- Montreal Cognitive Assessment (MoCA) score 21 or less, or inability to follow directions
- Excessive use of alcohol or recreational drugs
- Recent change in medication
- Inability to stand and walk for 2 minutes without an assistive device
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Arizona State University
Tempe, Arizona, United States, 85281
Actively Recruiting
2
Oregon Health and Science University
Portland, Oregon, United States, 97239
Actively Recruiting
3
University of São Paulo, Bauru Campus
Bauru, São Paulo, Brazil, 17012-230
Actively Recruiting
Research Team
G
Graham R Harker, MPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here