Actively Recruiting

Age: 18Years +
FEMALE
Healthy Volunteers
ID04579835

Twin A Breech External Cephalic Version Intervention Trial

Led by Charite University, Berlin, Germany · Updated on 2024-02-06

45

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to evaluate the use of external cephalic version (ECV) for managing Twin A breech presentation in twin pregnancies. The study seeks to determine the success rate of this procedure at an obstetric clinic and to identify new sonographic criteria that may predict successful ECV attempts, which have not been explored before. Participants will undergo the external cephalic version procedure targeting Twin A in the pregnancy. The study will monitor and assess various factors such as fetal weight, Doppler indices, and maternal and fetal outcomes shortly before and after the procedure. Follow-up will continue with evaluations including delivery mode six weeks after birth. During the study, participants will be assessed through ultrasound measurements, cardiotocogram monitoring, and pain scoring at specific intervals before and after the ECV procedure. Researchers will track outcomes such as emergency delivery, bleeding, contractions, and rupture of membranes. The primary outcome is the success rate of the ECV measured four hours after the procedure, with additional follow-up up to six weeks postpartum.

CONDITIONS

Brief Title

Twin A Breech External Cephalic Version Intervention Trial (TWEXIT)

Who Can Participate

Age: 18Years +
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Presence of written consent from the patient
  • Patients must be over 18 years old
  • No limit in the ability to consent
Not Eligible

You will not qualify if you...

  • Age under 18
  • Limited ability to consent
  • Placenta previa
  • Fetal abnormalities

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Implementation

Duration - Day of the procedure

Participants undergo External Cephalic Version for Twin A as part of the study procedures.

1 visit (in-person)

Monitoring

Duration - Up to 6 weeks after delivery

Participants are monitored for safety and outcomes up to 6 weeks after delivery.

1 visit 6 weeks after delivery and assessments immediately before and after the procedure

Trial Site Locations

Total: 1 location

1

Charité University Hospital

Mitte, Germany, 10117

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Research Team

L

Larry Hinkson, FRCOG

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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