Actively Recruiting

Phase 3
Age: 18Years - 65Years
All Genders
NCT05860868

Two Cycles VS Three Cycles Induction Chemotherapy in T1-4N2-3 Locally Advanced Nasopharyngeal Carcinoma

Led by First Affiliated Hospital, Sun Yat-Sen University · Updated on 2023-05-16

474

Participants Needed

1

Research Sites

365 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This trial is a multi-center phase III clinical trial. The purpose of this trial is to explore whether 2 cycles induction chemotherapy combined with concurrent chemoradiotherapy is not inferior to 3 cycles induction chemotherapy combined with concurrent chemoradiotherapy in patients with locally advanced nasopharyngeal carcinoma.

CONDITIONS

Official Title

Two Cycles VS Three Cycles Induction Chemotherapy in T1-4N2-3 Locally Advanced Nasopharyngeal Carcinoma

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 to 65 years old
  • Pathologically confirmed non-keratinizing nasopharyngeal carcinoma
  • Stage T3-4N0-1 according to UICC/AJCC 8th edition
  • No distant metastasis
  • No prior anti-cancer treatment
  • ECOG performance status of 0 or 1
  • Adequate blood, liver, and kidney function
Not Eligible

You will not qualify if you...

  • Treatment intended for palliative care
  • Diagnosed with other malignant tumors at the same time
  • History of malignant tumors
  • Pregnant, breastfeeding, or planning pregnancy during the trial
  • Presence of serious combined illness

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

First Affiliated Hospital, Sun Yat-Sen University

Guangzhou, Other (Non U.s.), China, 510080

Actively Recruiting

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Research Team

C

Cheng-Tao Wang

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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