Actively Recruiting

Phase Not Applicable
Age: 18Years - 45Years
All Genders
ID07351812

Evaluation of Two Treatment Modalities for Myogenous Temporomandibular Disorders: A Randomized Controlled Trial

Led by Alexandria University · Updated on 2026-01-20

32

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Temporomandibular disorder (TMD) is a common condition caused by many factors such as trauma, emotional stress, habits, and bite problems. It can affect the muscles involved in chewing (myogenous) or the joint structures (arthrogenous). This trial focuses on myogenous TMD and aims to compare two treatment methods: the widely used stabilization appliance (SA) and the newer ear stent (ES). Participants will be randomly assigned to one of two groups. The first group will receive a maxillary stabilization appliance made from hard thermoplastic material, worn for 3 months. The second group will receive a custom ear stent made from soft silicone, worn full-time except during meals, showering, or swimming. Before treatment, patients will have impressions taken and evaluations to ensure proper fit and safety. During the study, muscle activity of jaw muscles and mouth opening will be measured at the start and after 3 months to evaluate changes. Pain levels will also be tracked. Participants will undergo clinical assessments including dental impressions and ear exams. The study runs from January 2025 to June 2026 and is sponsored by Alexandria University.

CONDITIONS

Brief Title

Two Treatment Modalities for Myogenous Temporomandibular Disorders

Who Can Participate

Age: 18Years - 45Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants with jaw muscle pain scoring at least 4 out of 10 on the numeric rating scale
  • Fully dentate participants with type I occlusion
  • No neurological disorders present
Not Eligible

You will not qualify if you...

  • Patients with arthrogenous temporomandibular joint disorder as confirmed by MRI
  • Patients experiencing clicking or crepitation sounds in the jaw
  • Previous history of temporomandibular disorder treatment
  • History of recent trauma
  • Presence of systemic diseases such as rheumatoid arthritis, osteoarthritis, or other myologic or arthrological diseases
  • Vascular diseases including migraine and hypertension
  • Uncontrolled systemic diseases like diabetes, hematologic, neurologic, or inflammatory disorders
  • Patients who had trigger point myofascial injection, intramuscular stimulation, or dry needling within the last six months
  • Patients who underwent neck or shoulder surgery in the last year

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 3 months

Participants will receive either a maxillary stabilization appliance to wear for 3 months or a custom ear stent to wear full-time except during meals, showering, or swimming.

1 baseline visit and 1 follow-up visit after 3 months

Trial Site Locations

Total: 1 location

1

Alexandria Faculty of Dentistry

Alexandria, Egypt

Actively Recruiting

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Research Team

A

Alaa F Mohamed, BDS

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

Frequently Asked Questions

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