Actively Recruiting

Age: 18Years +
All Genders
ID06786364

Types of Photoplethysmographic Waves in Adult Patients with Septic Shock

Led by Hospital General de México Dr. Eduardo Liceaga · Updated on 2025-01-22

116

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are investigating the types of photoplethysmographic waves found in adults with septic shock to see if these wave types relate to other signs of poor blood flow, such as capillary refill, serum lactate levels, and mottling score. Photoplethysmography, used in pulse oximeters, produces waves that reflect blood flow and arterial tone, which can be categorized into six types indicating various levels of blood vessel constriction or dilation. This study uses a classification by Tusman and collaborators to identify wave types and their frequency in septic shock patients, aiming to understand their connection to hemodynamic factors like heart rate and blood pressure. The study observes adult patients diagnosed with septic shock who meet specific criteria such as temperature and ability to tolerate lying down. No experimental treatments are given as this is an observational study. Instead, researchers will record photoplethysmographic wave types and measure other variables like capillary refill, serum lactate, mottling score, heart rate, blood pressure, and perfusion index after patient inclusion. These assessments help to describe the vascular tone and tissue perfusion status in septic shock. Participants will undergo monitoring for the photoplethysmographic wave types and other clinical measurements after being enrolled. Data collection focuses on several hemodynamic and tissue perfusion markers to explore correlations. The main outcome is the identification of wave types in patients with septic shock. Secondary outcomes include capillary refill, mottling score, serum lactate, heart rate, blood pressure, and perfusion index. The study is planned to start in November 2024 and continue through May 2025, with no interventions or treatments administered as part of the trial.

CONDITIONS

Brief Title

Types of Photoplethysmographic Waves in Adult Patients with Septic Shock

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients aged 18 years or older diagnosed with septic shock according to Sepsis 3.0
  • Axillary temperature above 36°C
  • Patients and/or family members willing to participate and sign informed consent
  • Patients able to tolerate lying in a supine position
Not Eligible

You will not qualify if you...

  • Patients with cardiogenic, hypovolemic, obstructive, or distributive (neurogenic, anaphylactic) shock other than septic shock
  • History of any type of cardiac arrhythmia
  • History of chronic hepatic disease
  • Presence of limited or diffuse systemic sclerosis
  • Scarring, nail polish, or thickened nails that prevent accurate photoplethysmography measurement
  • History of heart insufficiency
  • Septic shock patients already receiving vasopressor agents

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Monitoring

Duration - After the inclusion of the participant

Participants are observed to identify the types of photoplethysmographic waves present and to collect related hemodynamic data.

Trial Site Locations

Total: 1 location

1

Hospital General de México Dr. Eduardo Liceaga

Mexico City, Cuauhtemoc, Mexico, 06726

Actively Recruiting

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Research Team

J

Juan Fernando Bautista Garcia, MD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Published Research Related To This Trial

Photoplethysmographic characterization of vascular tone mediated changes in arterial pressure: an observational study.

Gerardo Tusman, Cecilia M Acosta, Sven Pulletz...

https://pubmed.ncbi.nlm.nih.gov/30554338