Photoplethysmographic characterization of vascular tone mediated changes in arterial pressure: an observational study.
Gerardo Tusman, Cecilia M Acosta, Sven Pulletz...
https://pubmed.ncbi.nlm.nih.gov/30554338Actively Recruiting
Led by Hospital General de México Dr. Eduardo Liceaga · Updated on 2025-01-22
116
Participants Needed
1
Research Sites
4 weeks
Total Duration
Researchers are investigating the types of photoplethysmographic waves found in adults with septic shock to see if these wave types relate to other signs of poor blood flow, such as capillary refill, serum lactate levels, and mottling score. Photoplethysmography, used in pulse oximeters, produces waves that reflect blood flow and arterial tone, which can be categorized into six types indicating various levels of blood vessel constriction or dilation. This study uses a classification by Tusman and collaborators to identify wave types and their frequency in septic shock patients, aiming to understand their connection to hemodynamic factors like heart rate and blood pressure. The study observes adult patients diagnosed with septic shock who meet specific criteria such as temperature and ability to tolerate lying down. No experimental treatments are given as this is an observational study. Instead, researchers will record photoplethysmographic wave types and measure other variables like capillary refill, serum lactate, mottling score, heart rate, blood pressure, and perfusion index after patient inclusion. These assessments help to describe the vascular tone and tissue perfusion status in septic shock. Participants will undergo monitoring for the photoplethysmographic wave types and other clinical measurements after being enrolled. Data collection focuses on several hemodynamic and tissue perfusion markers to explore correlations. The main outcome is the identification of wave types in patients with septic shock. Secondary outcomes include capillary refill, mottling score, serum lactate, heart rate, blood pressure, and perfusion index. The study is planned to start in November 2024 and continue through May 2025, with no interventions or treatments administered as part of the trial.
CONDITIONS
Types of Photoplethysmographic Waves in Adult Patients with Septic Shock
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - After the inclusion of the participant
Participants are observed to identify the types of photoplethysmographic waves present and to collect related hemodynamic data.
Total: 1 location
1
Hospital General de México Dr. Eduardo Liceaga
Mexico City, Cuauhtemoc, Mexico, 06726
Actively Recruiting
J
Juan Fernando Bautista Garcia, MD
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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Gerardo Tusman, Cecilia M Acosta, Sven Pulletz...
https://pubmed.ncbi.nlm.nih.gov/30554338