Actively Recruiting

Age: 18Years +
All Genders
ID06786364

Types of Photoplethysmographic Waves in Adult Patients with Septic Shock

Led by Hospital General de México Dr. Eduardo Liceaga · Updated on 2025-01-22

116

Participants Needed

1

Research Sites

30 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying adult patients with septic shock to identify different types of photoplethysmographic waves and see if these waves relate to tissue blood flow problems. Photoplethysmography, used in pulse oximeters, creates waves that reflect blood flow and artery tone. This study uses a classification of six wave types that indicate varying levels of blood vessel tightening or widening and aims to understand these wave types in septic shock patients and their links to other health measures like capillary refill and serum lactate. The study observes the photoplethysmographic wave types in adults diagnosed with septic shock, classifying the waves based on arterial tone from vasoconstriction to severe vasodilation. It also examines how often each wave type appears and compares this with other measurements such as mottling score, heart rate, blood pressure, and perfusion index. There are no specific interventions or treatments being tested, as the focus is on wave pattern identification and correlation with clinical signs. Participants will undergo monitoring to record the photoplethysmographic waves shortly after inclusion. Researchers will collect data on various related clinical signs and lab values during the study. The main outcome measured is the type of photoplethysmographic wave observed after patients join the study. The participation involves evaluation of these waveforms and their association with tissue hypoperfusion markers, providing insights over the course of the patients' septic shock condition.

CONDITIONS

Official Title

Types of Photoplethysmographic Waves in Adult Patients with Septic Shock

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients of 18 years of age and above diagnosed with septic shock according to the definition stated in Sepsis 3.0
  • Patients with axillary temperature above 366C
  • Patients and/or family that agree to participate in such study and sign the informed consent
  • Patients that tolerate supine position
Not Eligible

You will not qualify if you...

  • Patients with cardiogenic, hypovolemic, obstructive, and distributive (neurogenic, anaphylactic) shock except septic shock
  • Patients with history of any type of cardiac arrhythmia
  • Patients with history of chronic hepatic disease
  • Patients with limited or diffuse systemic sclerosis
  • Patients with scarring, nail polish, or thickened nails that may impede proper photoplethysmography measurement
  • Patients with history of heart insufficiency
  • Patients with septic shock already receiving vasopressor agents

AI-Screening

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Trial Site Locations

Total: 1 location

1

Hospital General de México Dr. Eduardo Liceaga

Mexico City, Cuauhtemoc, Mexico, 06726

Actively Recruiting

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Research Team

J

Juan Fernando Bautista Garcia, MD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Published Research Related To This Trial

Photoplethysmographic characterization of vascular tone mediated changes in arterial pressure: an observational study.

Gerardo Tusman, Cecilia M Acosta, Sven Pulletz...

https://pubmed.ncbi.nlm.nih.gov/30554338