Actively Recruiting
UAB Alzheimer's Disease Center Core Cohort - Imaging Substudy
Led by University of Alabama at Birmingham · Updated on 2025-12-11
160
Participants Needed
1
Research Sites
545 weeks
Total Duration
On this page
Sponsors
U
University of Alabama at Birmingham
Lead Sponsor
N
National Institute on Aging (NIA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The primary objective of this study is to measure the concentration and the regional brain distribution of pathologic amyloid deposition using the PET tracer \[C-11\]PiB in participants in the UAB Alzheimer's Disease Center cohort. Assessment of interactions between race and vascular risk factors, brain amyloid levels measured with \[C-11\]PiB-PET, and cognitive status will be the primary outcome of this imaging study.
CONDITIONS
Official Title
UAB Alzheimer's Disease Center Core Cohort - Imaging Substudy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Enrollment in the UAB-ADC study under a separate IRB-approved research protocol (IRB-300000169).
- Negative urine or serum B-hCG test within 2 days of [C-11]PiB administration in women of child bearing potential.
- Women who are post-menopausal with at least 1 year since last menses or documented surgical sterilization do not require pregnancy testing.
You will not qualify if you...
- Meets any exclusion criteria for the UAB-ADC study (IRB-300000169).
- Inability or contraindication for undergoing MRI and/or PET imaging.
- Inability to participate in the imaging studies due to severity of dementia.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Alabama at Birmingham Medical Center
Birmingham, Alabama, United States, 35294
Actively Recruiting
Research Team
C
Chinara Dosse
CONTACT
E
Evan Hudson
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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