Actively Recruiting
Udall Project 2 Aim 2A&C
Led by University of Minnesota · Updated on 2026-03-03
36
Participants Needed
1
Research Sites
269 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This protocol will leverage the novel (on-label, FDA-approved) local field potential measuring capability of the Medtronic Percept™ PC or RC DBS system to study the effects of globus pallidus internus, globus pallidus externus (GPi, GPe), and subthalamic nucleus (STN) DBS on: the wash-out and wash-in dynamics of motor behavior and local field potentials (LFPs) and correlations between fluctuations in gait and LFPs during activities of daily living (recorded over a minimum of 4 weeks). These experiments will elucidate the relationships between LFPs oscillations, lower limb function, postural control and gait performance.
CONDITIONS
Official Title
Udall Project 2 Aim 2A&C
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Receiving DBS therapy in GP for treatment of PD
- Implanted with Medtronic Percept DBS system
- At least 3 months since initial activation of the neurostimulator
- For the "At Home" experiment only: participants with DBS settings that are sensing compatible.
You will not qualify if you...
- History of musculoskeletal disorders that significantly affects the ability to perform the motor tasks in the specific experiment in question
- History of dementia or cognitive impairment
- Other significant neurological disorder as determined by the PI
- Post-operative complications or adverse effects (e.g. ON stimulation dystonias) that affect patient safety or confound the experiment
- Lack of capacity to consent (as identified by MaCAT-CR)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Minnesota
Minneapolis, Minnesota, United States, 55414
Actively Recruiting
Research Team
C
Colum Mackinnon, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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