Actively Recruiting

Age: 6Years - 18Years
All Genders
NCT05554016

The UFO (Ultra Processed Foods in Obesity) Project

Led by Federico II University · Updated on 2025-06-04

200

Participants Needed

1

Research Sites

178 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The childhood obesity prevalence has increased dramatically in the last decades, affecting more than 340 million children worldwide. This condition is the major risk factor for a set of metabolic abnormalities, also known as metabolic syndrome, a condition that reduce life expectancy by 5-20 years. Changes in the global food system, and the increased consumption of ultra-processed foods (UPFs), may have contributed to the increase in the prevalence of childhood obesity and related morbidities. The mechanisms by which UPFs might promote obesity and metabolic syndrome could be multiple and not completely identified. The Ultra-processed Food in Obesity (UFO) Project has been designed to investigate the potential associations between UPFs intake and MetS in pediatric subjects

CONDITIONS

Official Title

The UFO (Ultra Processed Foods in Obesity) Project

Who Can Participate

Age: 6Years - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Caucasian ethnicity
  • Both sexes
  • Age between 6 and 18 years
  • Diagnosis of obesity (Group 1)
  • Diagnosis of obesity and metabolic syndrome (Group 2)
  • Age- and sex-matched healthy controls (Group 3)
Not Eligible

You will not qualify if you...

  • Non-Caucasian ethnicity
  • Age less than 6 or greater than 18 years
  • Presence of chronic diseases, neoplasms, immunodeficiencies, chronic infections, autoimmune diseases, chronic inflammatory bowel disease, celiac disease, metabolic-genetic diseases, cystic fibrosis, and other chronic lung diseases
  • Cardiovascular, respiratory, or gastrointestinal malformations
  • Neuropsychiatric or neurological disorders
  • Recent intake of antibiotics and/or pre/pro/synbiotics
  • History of obesity surgery
  • Onset of diarrhea or acute gastrointestinal illness within 12 weeks prior to enrollment
  • Presence of tattoos, scars, moles, or special lesions on both forearms

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Department of Traslational Medical Science - University of Naples Federico II

Naples, Italy, 80131

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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