Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID06360627

Ultra Low Dose CT and Use of Iomeron 400 in PCD-CT

Led by University of Zurich · Updated on 2024-04-11

100

Participants Needed

1

Research Sites

35 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This trial evaluates ultra low dose computed tomography (CT) scan protocols and the use of Iomeron 400 contrast in photon-counting detector CT (PCD-CT) imaging. It focuses on participants needing CT scans for lung conditions such as pulmonary nodules, pneumonia, lung embolism, or lung cancer. The study aims to compare radiation dose reduction while maintaining image quality in these scans. Participants will undergo either a standard low dose CT scan or an ultra low dose CT scan using the new PCD-CT technology with Iomeron 400 contrast. The study is non-randomized and open-label, meaning participants know which scan protocol they receive. The primary focus is on dose reduction and image quality over about one year of follow-up. During the study, participants will have chest CT scans to detect or monitor lung issues. Researchers will assess radiation dose reduction achieved by the new scanner and monitor image quality stability during reduced dose scans. The total study duration is approximately one year, and safety and scan effectiveness are tracked throughout this period.

CONDITIONS

Brief Title

Ultra Low Dose CT and Use of Iomeron 400 in PCD-CT

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • CT scan for pulmonary nodule detection or follow-up
  • CT scan for pneumonia detection or follow-up
  • Age 18 years or older
Not Eligible

You will not qualify if you...

  • Under 18 years of age
  • Body mass index (BMI) over 30

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Up to 1 year

Participants undergo computed tomography scans using either standard low dose or ultra low dose settings to evaluate pulmonary conditions.

1 or more visits depending on clinical need

Trial Site Locations

Total: 1 location

1

University Hospital Zurich - Diagnostic Radiology

Zurich, Switzerland, 8091

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

DIAGNOSTIC

Number of Arms

2

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