Actively Recruiting
Ultra Low Dose Radiation Therapy in Treating Patients With Mycosis Fungoides
Led by M.D. Anderson Cancer Center · Updated on 2026-04-15
50
Participants Needed
1
Research Sites
520 weeks
Total Duration
On this page
Sponsors
M
M.D. Anderson Cancer Center
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This phase II trial studies how well ultra low dose radiation therapy works in treating patients with mycosis fungoides. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Giving ultra low doses of radiation may help control the disease and reduce side effects compared to treatment with higher doses.
CONDITIONS
Official Title
Ultra Low Dose Radiation Therapy in Treating Patients With Mycosis Fungoides
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with pathologically confirmed mycosis fungoides involving the skin.
- Patients must have at least one clinically measurable skin lesion.
- New lesions diagnosed clinically without biopsy are eligible if prior MF diagnosis exists.
- Eligible lesions must have a height of 1 cm or less.
- Patients with all disease stages (IA through IVB) are eligible if radiation is considered for local control.
- Patients receiving systemic therapy for advanced disease may participate.
- Female patients able to become pregnant must have a negative pregnancy test within 2 weeks of enrollment or sign a declaration stating they are not pregnant.
- Use of topical chemotherapy, retinoids, or imiquimod on the enrolled lesion must be stopped at least 24 hours before enrollment.
- Patients using topical treatments on other lesions not enrolled can still participate.
You will not qualify if you...
- Pregnant patients are not eligible for radiation therapy.
- Patients with active lupus or scleroderma are excluded.
- Lesions taller than 1 cm from the skin surface are not eligible.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
M D Anderson Cancer Center
Houston, Texas, United States, 77030
Actively Recruiting
Research Team
B
Bouthaina Dabaja, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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