Actively Recruiting
Ultra-protective Ventilation Monitored by Electrical Impedance Tomography in Patients With Severe Acute Respiratory Distress Syndrome on Veno-venous ECMO
Led by Assistance Publique - Hôpitaux de Paris · Updated on 2025-05-15
50
Participants Needed
1
Research Sites
217 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
For ECMO supported patients with severe ARDS (acute respiratory distress syndrome), usual care include use of "ultraprotective" mechanical ventilation with tidal volume and pressure reductions that might ultimately enhance lung protection of patients with ARDS. Although very low tidal might also cause pulmonary derecruitment. The aim of this study is to monitor effects of very low tidal volume on regression of overdistension and derecruitment using electrical impedance tomography. Secondary aim is to describe the evolution of the optimal PEEP (Positive End Expiratory Pressure) during the decrease of the tidal volume
CONDITIONS
Official Title
Ultra-protective Ventilation Monitored by Electrical Impedance Tomography in Patients With Severe Acute Respiratory Distress Syndrome on Veno-venous ECMO
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 18 years or older
- Diagnosed with ARDS and receiving venovenous ECMO support
- Able to provide written informed consent
- Affiliated with a social security scheme
You will not qualify if you...
- Pregnancy
- Under legal protection measures (such as tutor or curator)
- Presence of a pacemaker or automatic implantable cardioverter defibrillator
- Contraindications to thoracic belt placement (for example, chest or spinal trauma, recent chest surgery)
- Undrained pneumothorax or bronchopleural fistula
- Hemodynamic instability requiring high doses of intravenous fluids or vasopressors
AI-Screening
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Trial Site Locations
Total: 1 location
1
Service de médecine intensive - réanimation Hopital Pitié Salpêtrière
Paris, France, 75013
Actively Recruiting
Research Team
M
Matthieu Pr SCHMIDT
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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