Actively Recruiting
ULtrafiltration-Rate Induced CArdiac Strain (ULRICA) - Study
Led by Umeå University · Updated on 2024-12-16
40
Participants Needed
1
Research Sites
162 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Patients performing chronic hemodialysis (HD) retain more or less water between dialyses. The water is removed by ultrafiltration and usually during the cleansing of waste products - the HD. The length of HD is usually the same as the time of fluid removal while sometimes this may differ. There is no clear guideline. In previous research the investigator noted that the heart releases more NT-pro-BNP during HD in numerous of the patients. The present study aims to clarify if the speed of fluid removal during HD is a factor that may alter the release of cardiac markers during HD. If so the recommendations for the prescription of HD can be updated.
CONDITIONS
Official Title
ULtrafiltration-Rate Induced CArdiac Strain (ULRICA) - Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult HD patients with an intra-dialytic weight gain (IDWG) 652.5% of target weight over the long interval (3 days) prior to inclusion.
- Patients need to be able to understand the study information
- Patients need to be able to give consent.
You will not qualify if you...
- Active systemic inflammatory state such as extensive malignancy or acute septic infection.
- Uncontrolled hyperphosphatemia as decided by the local physician's routine (due to decreased efficacy of the low flux filter to eliminate phosphate).
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Region Vasterbotten, Norrlands Universitetssjukhus, Dialysen
Umeå, Sweden, SE90185
Actively Recruiting
Research Team
B
Bernd Stegmayr, MD, PhD
CONTACT
M
Michael Ott, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
CROSSOVER
Primary Purpose
PREVENTION
Number of Arms
2
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