Actively Recruiting
Ultralow Dose PET Imaging of SSTR2 Radiotracer Uptake
Led by Akiva Mintz · Updated on 2026-04-08
200
Participants Needed
1
Research Sites
228 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to evaluate an investigational ultralow dose positron emission tomography (PET) imaging technique for neuroendocrine tumor detection and monitoring. The main question it aims to answer is: Can the investigators optimize the timing, scan duration, and image reconstruction to reduce the radiation dose 10-100 fold of the current clinical standard? Participants will be injected with a radioactive tracer that binds to a tumor specific protein called somatostatin receptor 2 (SSTR2) and be imaged on a new type of high sensitivity PET scanner for up to 3 hours
CONDITIONS
Official Title
Ultralow Dose PET Imaging of SSTR2 Radiotracer Uptake
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Ability to provide informed consent and comply with study procedures
- For female participants: Must not be pregnant or breastfeeding; Negative pregnancy test required for women of childbearing potential
You will not qualify if you...
- Exceeded NRC regulation for annual radiation exposure from prior research scans, including this study (over 50 millisievert total)
- More than four prior enrollments in this study
- Severe claustrophobia, chronic pain, or musculoskeletal conditions preventing PET scan completion
- Prior treatment with SSTR targeted therapies
- Pregnant or breastfeeding individuals (negative pregnancy test required)
- Inability to provide informed consent
- Any condition compromising participant safety or study integrity according to investigator judgment
AI-Screening
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Trial Site Locations
Total: 1 location
1
Nuclear Imaging Institute
Englewood, New Jersey, United States, 07631
Actively Recruiting
Research Team
B
Barbara Blanchfield
CONTACT
D
Dianna Willis, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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