Testing Ultrasonication-Mediated Microbubbles Dressing with Piroxicam Gel for Treating Hand Arthritis in Adults

What this Trial Is About

Researchers are evaluating the effect of an ultrasonication-mediated microbubbles dressing combined with piroxicam gel for treating hand arthritis in adults. The study aims to find out if adding this dressing improves treatment effectiveness and to assess its safety. Participants with hand arthritis will be compared across three groups to see which approach works best. The trial has three groups one uses the microbubbles dressing with piroxicam gel, applied on specific days the second uses ultrasonication with pure gel plus piroxicam gel and the third uses piroxicam gel alone for one week. Ultrasonication treatments occur on days 1, 3, and 5, while piroxicam gel is applied on days 2, 4, 6, and 7 or daily for the gel-only group. Participants will visit the clinic on day 1 and day 8 for checkups and tests. They will keep a symptom diary throughout the week. Researchers will measure clinical responses and imaging responses using B-mode and power Doppler on day 8 to evaluate treatment effects and safety. The study is randomized with single masking and led by National Taiwan University.

Ultrasonication-mediated Microbubbles Dressing for Hand Arthritis