Actively Recruiting
Ultrasonographic Assessment of Muscle Morphology, Function, and Clinical Findings in Spastic Cerebral Palsy
Led by Kocaeli University · Updated on 2026-02-03
36
Participants Needed
1
Research Sites
28 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study focuses on children with spastic cerebral palsy and aims to examine how muscle morphology and tissue characteristics, as assessed by ultrasound, may relate to functional motor abilities. It is designed as a prospective, cross-sectional, observational study. Planned ultrasound-based assessments include parameters such as muscle thickness, pennation angle, fascicle length, echo intensity, tissue stiffness (via shear wave elastography), and microvascular flow (via superb microvascular imaging). These measurements are intended to be compared with standard clinical evaluations, including the GMFCS, GMFM-66, MAS, MACS, and Tardieu Scale. The study seeks to contribute to a better understanding of the relationship between muscle architecture and functional outcomes, with the goal of generating insights that may inform individualized rehabilitation planning.
CONDITIONS
Official Title
Ultrasonographic Assessment of Muscle Morphology, Function, and Clinical Findings in Spastic Cerebral Palsy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of spastic cerebral palsy according to Rosenbaum et al. (2007)
- Age between 4 and 18 years
- Gross Motor Function Classification System (GMFCS) Level I, II, or III
- Manual Ability Classification System (MACS) Level I, II, III, or IV
You will not qualify if you...
- Non-spastic types of cerebral palsy (e.g., dyskinetic, ataxic)
- Neuromuscular disorders other than cerebral palsy (e.g., hereditary neuropathy, myopathy)
- Muscle contractures or fixed deformities in limbs selected for assessment
- Cognitive or behavioral impairments preventing cooperation during evaluations
- Botulinum toxin-A injection to target muscles within last 6 months
- Current treatment with oral or intrathecal antispastic medications
- History of orthopedic surgery or selective dorsal rhizotomy involving target muscles
- Acute infection, febrile illness, or severe systemic disease compromising safety of assessments
AI-Screening
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Trial Site Locations
Total: 1 location
1
Kocaeli University Faculty of Medicine
Kocaeli, Turkey (Türkiye)
Actively Recruiting
Research Team
M
Mustafa Kadıoğlu, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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