Actively Recruiting
Evaluation of Inferior Vena Cava and Femoral Vein Collapsibility Indices to Predict Post-Spinal Hypotension in Patients Undergoing Transurethral Prostate Resection
Led by Antalya Training and Research Hospital · Updated on 2026-03-27
110
Participants Needed
1
Research Sites
6 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to evaluate how well ultrasound-based measurements of the inferior vena cava collapsibility index (IVC-CI) and femoral vein collapsibility index (FVCI) can predict low blood pressure after spinal anesthesia in men undergoing elective transurethral prostate resection (TUR-P). Post-spinal hypotension is a common and serious complication, especially in older patients, caused by reduced vascular tone and venous return. Identifying patients at risk could help improve safety during surgery. Before spinal anesthesia, eligible adult male patients will undergo ultrasound measurements of the IVC and femoral vein while lying down. No fluid preload will be given before anesthesia. Standard monitoring including ECG, oxygen levels, and blood pressure will be used. After spinal anesthesia, blood pressure and heart rate will be recorded every two minutes for 15 minutes. Patients will be grouped based on whether they develop hypotension according to specific blood pressure criteria. Participants will be assessed through ultrasound scans, continuous hemodynamic monitoring, and standard clinical evaluations. Researchers will compare the accuracy of IVC-CI and FVCI in predicting hypotension and look for additional clinical factors related to this risk. The main outcome is the occurrence of hypotension within 15 minutes after spinal anesthesia. This study will help determine a noninvasive method to predict and manage post-spinal hypotension in TUR-P patients.
CONDITIONS
Brief Title
Ultrasound Assessment of Femoral Vein and Inferior Vena Cava Collapsibility to Predict Spinal Anesthesia-Induced Hypotension
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult male patients aged 18 to 75 years
- Physical status classified as ASA I to III
- Scheduled for elective transurethral resection of the prostate (TUR-P)
- Planned spinal anesthesia
- Ability to provide written informed consent
You will not qualify if you...
- Refusal to participate in the study
- Body mass index (BMI) greater than 30 kg/m²
- Current use of angiotensin-converting enzyme inhibitors or angiotensin receptor blockers
- Emergency surgery
- Baseline systolic arterial blood pressure below 90 mmHg or mean arterial pressure below 70 mmHg
- Major peripheral vascular disease or severe cardiovascular disease
- Unstable angina or left ventricular ejection fraction less than 40%
- Chronic respiratory disease
- Increased intra-abdominal pressure
- Autonomic nervous system disorders
- Implanted pacemaker or implantable cardioverter-defibrillator
- Anticipated difficult airway
- Cognitive impairment or inability to cooperate
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of surgery
Participants undergo ultrasonographic assessment of the inferior vena cava and femoral vein to measure collapsibility indices before spinal anesthesia.
1 visit (in-person)
Duration - 15 minutes
After spinal anesthesia, participants' hemodynamic parameters are monitored at two-minute intervals for 15 minutes to detect post-spinal hypotension.
Continuous monitoring during the surgery visit
Trial Site Locations
Total: 1 location
1
University of Health Sciences, Antalya Training and Research Hospital
Antalya, Muratpasa, Turkey (Türkiye), 07030
Actively Recruiting
Research Team
S
Semsettin Ekingen, Medical Doctor
K
Kerem Inanoglu, Medical Doctor
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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