Actively Recruiting
Ultrasound and Cytological Evaluation 3 Years After Radiofrequency Thermal Ablation of Benign Thyroid Nodules : a Prospective Exploratory Cohort of 180 Nodules
Led by Assistance Publique - Hôpitaux de Paris · Updated on 2025-09-03
180
Participants Needed
1
Research Sites
143 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
There is no scientific data on post-thermal ablation cytological aspects, but treated nodules that grow back significantly after a procedure justify a new cytology in order not to ignore a neoplastic process. The EU-TIRADS classification usually used to stratify the risk of cancer (and to justify a fine needle aspiration biopsy) of thyroid nodules is not validated for nodules treated by thermal ablation (TA) (post-RF nodules). However, these nodules often acquire ultrasound criteria of suspicion making it necessary to develop an ultrasound stratification of the risk of malignancy specific to nodules treated by TA. The objective of this work is to describe the ultrasound and cytological aspects of these treated nodules by performing a systematic assessment at 3 years after thermal ablation including systematic neck ultrasound and fine needle aspiration biopsy. Thus, an ultrasound and cytological atlas (Bethesda classification 2017) of nodules treated by thermal ablation will be constituted.
CONDITIONS
Official Title
Ultrasound and Cytological Evaluation 3 Years After Radiofrequency Thermal Ablation of Benign Thyroid Nodules : a Prospective Exploratory Cohort of 180 Nodules
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients older than 18 years
- Have a benign thyroid nodule treated by radiofrequency thermal ablation about 36 months (plus or minus 12 months) ago, regardless of nodule size changes
- Able to provide written informed consent
- Affiliated with a social security system (excluding AME)
You will not qualify if you...
- Pregnant or breastfeeding women
- Previous use of alcohol for treatment
- Taking anti-vitamin K anticoagulants
- Taking direct oral anticoagulants
- Persons deprived of liberty by judicial or administrative decision
- Persons under forced psychiatric care
- Persons admitted to a health or social institution for reasons other than research
- Adults under legal protection (guardianship or curatorship)
- Persons unable to provide consent
- Persons under any legal protection measure without exceptions
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Hospital Pitié-Salpêtrière - Department of Thyroid and Endocrine Tumour Pathologies
Paris, France, 75651
Actively Recruiting
Research Team
A
Adrien BEN HAMOU, MD-PhD
CONTACT
C
Camille BUFFET, MD-PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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