Evaluation of Heart Function Using Ultrasound During Three Types of Breathing Trials in ICU Patients on Mechanical Ventilation

What this Trial Is About

Researchers are evaluating the changes in a cardiac ultrasound index called EE during three different spontaneous breathing trials in adults in the Intensive Care Unit ICU who are at risk for difficulty when stopping mechanical ventilation. The study aims to determine which breathing trial puts the least strain on the heart by comparing the effects of the three trials when performed in a random order. The study involves three types of spontaneous breathing trials a humidified high flow trial with a ventilator set at 50 liters per minute, a trial with no pressure support and no positive end-expiratory pressure PEEP for 15 minutes, and a trial with pressure support set at 7 cmH2O and PEEP at 0 cmH2O for 15 minutes. Between breathing trials, participants have a 10-minute break to recover. The trials are performed while patients are connected to the ventilator or its specific setup for humidified flow. Participants will simply breathe without respiratory support during each trial while the researchers perform cardiac ultrasound measurements at the 5th minute of each 15-minute trial to assess heart function. The main measurement is the EE index from ultrasound. This study lasts through the duration of the three trials with monitoring and assessments done during each trial to understand the hearts workload under different breathing conditions.

Ultrasound Evaluation of Cardiac Function During Spontaneous Breathing Trials