Actively Recruiting
Ultrasound Features of Dupuytren's Disease
Led by Universitaire Ziekenhuizen KU Leuven · Updated on 2026-03-16
20
Participants Needed
1
Research Sites
101 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Dupuytren's disease (DD) is a benign and progressive condition that affects the palmar aponeurosis with a very high global incidence. It can result in significant loss of hand function or can inhibit an individual's daily activities or work. Current diagnostics rely on Range Of Motion (ROM) measurements and clinical expertise, where the decision for treatment is primarily based on patient preferences with little scientific research supporting different options in different cases. With technological advancements new options arise to the possible diagnostic tools that can be used for evidence based medicine and shared decision making. One option comes to light for DD because of its cheap, non -invasive and no radiation load, namely ultrasound (US). The use of US for DD is not standard care, due to the lack of research surrounding this tool. This study will provide some insight into the use of US for DD and will primarily try to evaluate different parameters measurable with US that can be used as potential prognostic biomarkers.
CONDITIONS
Official Title
Ultrasound Features of Dupuytren's Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Voluntary written informed consent obtained before screening
- Clinical diagnosis of Dupuytren's disease with Tubiana stage II or less (TPED ≤ 90°)
- Soft Dupuytren's nodules confirmed by a hand surgeon
- Self-reported recent rapid disease progression or new/discomforting symptoms
- Agreement to avoid surgical treatment for Dupuytren's disease during 6 months of participation
- Willingness to return for follow-up measurements after 6 months
You will not qualify if you...
- Any other hand or finger disorder affecting ultrasound quality (e.g., trigger finger, fracture, hematoma, tenosynovitis, tendon ruptures, scleroderma, fibromatosis, inflammatory conditions, rheumatoid arthritis, osteoarthritis)
- Prior treatment for Dupuytren's disease in the affected hand (needle fasciotomy, fasciectomy)
- Affected finger with TPED over 90° (Tubiana stage III)
- Undergoing treatment for Dupuytren's disease during the study (e.g., fasciectomy, fasciotomy, stretching braces, collagenase injections)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Universitaire Ziekenhuizen KU Leuven
Leuven, Vlaams-Brabant, Belgium, 3000
Actively Recruiting
Research Team
I
Ilse Degreef, Prof. Dr.
CONTACT
A
Anna Tarasiuk
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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