Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
ID07535697

Prospective, Randomized Study Comparing Ultrasound-Guided Erector Spinae Plane Block and Thoracoscopically-Guided Intercostal Nerve Block in Video-Assisted Thoracoscopic Surgery for Postoperative Pain

Led by Sana Klinikum Offenbach · Updated on 2026-05-01

72

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Effective pain management after thoracic surgery is crucial to prevent breathing difficulties and reduce the risk of lung complications such as atelectasis or pneumonia. This research compares two regional anesthesia methods used to manage pain after minimally invasive lung surgery called video-assisted thoracoscopic surgery (VATS) in adults. It aims to determine if an ultrasound-guided erector spinae plane block (ESPB) offers similar pain relief and opioid use compared to a thoracoscopically-guided intercostal nerve block (ICNB).

CONDITIONS

Brief Title

Ultrasound-Guided Erector Spinae Plane Block Versus Thoracoscopically-Guided Intercostal Nerve Block in Video-Assisted Thoracoscopic Surgery

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Provision of written informed consent
  • Adults 18 years of age or older
  • Scheduled for elective video-assisted thoracoscopic surgery (VATS) for pulmonary resection such as lobectomy, segmentectomy, or wedge resection
Not Eligible

You will not qualify if you...

  • Lack of informed consent
  • Language barrier
  • Pregnancy or breastfeeding
  • Known allergy to local anesthetics used in the study
  • Infection at the injection site(s)
  • History of complex chest wall surgery
  • Revision surgery within the last 6 months
  • Intraoperative conversion to open thoracotomy
  • Chronic pain syndrome
  • Fibromyalgia
  • Chronic opioid use
  • Chronic alcohol abuse
  • Chronic substance abuse (e.g., THC, amphetamines, cocaine)
  • History of psychiatric disorders such as depression or schizophrenia
  • Impaired consciousness, cognition, or ability to communicate
  • Known coagulopathy or abnormal blood clotting tests
  • Ongoing therapeutic anticoagulation therapy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - Perioperative period on the day of surgery

Participants receive either an ultrasound-guided erector spinae plane block before general anesthesia or a thoracoscopically-guided intercostal nerve block during surgery to manage postoperative pain.

1 surgical visit (in-person)

Follow-up

Duration - 24 hours post-surgery

Participants are monitored for postoperative pain and analgesic consumption within the first 24 hours after surgery.

1 follow-up visit (in-person)

Trial Site Locations

Total: 1 location

1

Sana Klinikum Offenbach

Offenbach, Hesse, Germany, 63069

Actively Recruiting

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Research Team

P

Prof. Dr. H. Mutlak

E

E. Park, MD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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