Actively Recruiting
Ultrasound-Guided Microwave Ablation Vs. Surgery for Low-Risk PapilaryThyroid Carcinoma
Led by Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Updated on 2024-12-31
201
Participants Needed
1
Research Sites
165 weeks
Total Duration
On this page
Sponsors
S
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Lead Sponsor
N
National Natural Science Foundation of China
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study aims to investigate the efficacy and prognosis of ultrasound-guided and gene-based microwave ablation (MWA) versus surgical treatment in patients with low-risk papillary thyroid carcinoma (PTC). By analyzing genetic testing results, the study explores the impact of genetic mutations on treatment selection for low-risk patients, providing more precise molecular biological evidence for treatment choices and prognosis evaluation of thyroid cancer. This prospective study collects clinical data from patients diagnosed with PTC at Sun Yat-sen Memorial Hospital of Sun Yat-sen University between January 2022 and November 2024, who underwent genetic testing prior to treatment, and assesses efficacy and complications through long-term follow-up.
CONDITIONS
Official Title
Ultrasound-Guided Microwave Ablation Vs. Surgery for Low-Risk PapilaryThyroid Carcinoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Papillary thyroid carcinoma confirmed by fine-needle aspiration (FNA)
- Confirmed low-risk mutation types by next-generation sequencing (NGS) before surgery
- No severe functional diseases such as heart failure, severe respiratory diseases, or renal failure
- Availability of complete follow-up data
You will not qualify if you...
- Presence of local or distant metastasis as assessed by imaging including ultrasound or CT
- No preoperative genetic testing or inability to assess genetic test results
- Inability to complete follow-up or lost to follow-up during the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Guangzhou, Guangdong, China, 510030
Actively Recruiting
Research Team
M
Miaoyun Long, MD
CONTACT
Y
Yuxin Shen, MBBS
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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