Actively Recruiting
Ultrasound-guided Modified Transversus Thoracic Muscle Plane Block and Erector Spinal Muscle Plane Block in Heart Valve Replacement Surgery With Median Incision
Led by Le Yu · Updated on 2024-06-21
60
Participants Needed
1
Research Sites
9 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Sternum midline incision can offer better view under open-heart surgery and bigger operating space, and therefore it has been widely used in most cardiac surgery. If an event of urgency occurs, it takes on a more important role than infrasternal small incision. However, sternum midline incision may cause serious pain and aggravates stress response, and therefore patients are often reluctant to cooperate to cough which exerts adverse effect on postoperative rehabilitation, and even causes serious complications such as pulmonary inflammation, myocardial infarction and heart failure. Thus, the relief of pain and better perioperative analgesia are very important for these patients. Transversus thoracic muscle plane(TTMP) block and erector spinal muscle plane(ESP) block are used in open heart surgery currently, and they can provide good analgesia. This study aimed to investigate the hemodynamic stability, total amount of analgesic use, perioperative pain, stress response, postoperative complication and recovery in patients receiving TMP and ESP.
CONDITIONS
Official Title
Ultrasound-guided Modified Transversus Thoracic Muscle Plane Block and Erector Spinal Muscle Plane Block in Heart Valve Replacement Surgery With Median Incision
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 18 to 75 years
- Body mass index (BMI) between 18 and 25 kg/m2
- American Society of Anesthesiologists (ASA) physical status I-II
- New York Heart Association (NYHA) class I-II
- Scheduled for mitral valve or aortic valve replacement surgery
You will not qualify if you...
- Undergoing a second operation
- Preoperative ejection fraction (EF) less than 40%
- Complicated coronary heart disease
- Receiving intra-aortic balloon counterpulsation (IABP) support
- Psychiatric abnormalities
- History of allergy to anesthetic drugs
- Liver or kidney dysfunction
- Coagulation abnormalities
- Endocrine system diseases
- Metabolic diseases
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Shanghai East Hospital of Tongji University
Shanghai, Shanghai Municipality, China, 200120
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
3
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