Actively Recruiting
Ultrasound-guided Multilevel Erectorspinae Plane Block Versus Thoracic Epidural Analgesia for Prevention of Post Mastectomy Pain Syndrome for Breast Cancer Patients
Led by National Cancer Institute, Egypt · Updated on 2025-05-21
44
Participants Needed
1
Research Sites
49 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of this study is to compare the analgesic efficacy of multilevel erector spinae plane block (ESPB) vs thoracic epidural in modified radical mastectomy (MRM) regarding duration of analgesia, postoperative opioid consumption, effect on intraoperative fentanyl consumption, postoperative numerical pain rating scale and quality of life for the next 6 months.
CONDITIONS
Official Title
Ultrasound-guided Multilevel Erectorspinae Plane Block Versus Thoracic Epidural Analgesia for Prevention of Post Mastectomy Pain Syndrome for Breast Cancer Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female patients age 64 18 years and 64 65 years
- Scheduled for Modified Radical Mastectomy (MRM) surgery
- Physical status ASA II or III
- Body mass index (BMI) greater than 20 kg/m2 and less than 35 kg/m2
You will not qualify if you...
- Patient refusal to participate
- Allergy or contraindication to drugs used in the study such as local anesthetics or opioids
- History of psychological disorders
- History of chronic pain
- Contraindications to regional anesthesia such as sepsis, peripheral neuropathies, or coagulopathy
- Advanced chronic kidney disease with a glomerular filtration rate less than 30 ml/min (stages 4 and 5)
- Decompensated liver cirrhosis characterized by serious liver complications
- Severe heart disease classified as NYHA class III or IV
- Severe lung disease including low oxygen saturation (less than 92%), high respiratory rate (more than 20), or FEV1/FVC ratio less than 60%
- Pregnancy
AI-Screening
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Trial Site Locations
Total: 1 location
1
National Cancer Institute
Cairo, Egypt, 11796
Actively Recruiting
Research Team
A
Ahmed El Abdelaal, Master
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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