Actively Recruiting

Phase Not Applicable
Age: 21Years +
FEMALE
ID06548646

Ultrasound-guided Thoracic Interfascial Plane Block versus Erector Spinae Plane Block for Pain Control After Modified Radical Mastectomy in Patients Undergoing Breast Cancer Surgery

Led by Safie ramez tewfeik abd el moneim · Updated on 2025-01-13

50

Participants Needed

1

Research Sites

19 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating two methods of local pain control for women undergoing Modified Radical Mastectomy, a common surgery to treat breast cancer. The study compares the Thoracic Interfascial Plane Block (TIPB) and the Erector Spinae Plane Block (ESPB), aiming to find which provides better pain relief, fewer side effects, and improved patient satisfaction after surgery. Managing pain effectively is important to reduce the use of opioids, which can cause unwanted side effects like nausea and drowsiness, and to help patients recover faster. Participants will be randomly assigned to receive either the TIPB or ESPB nerve block before surgery. Both procedures involve injecting a local anesthetic under ultrasound guidance to numb specific nerves in the chest and upper abdominal area. TIPB includes blocks targeting the pectoral and serratus muscles, while ESPB targets the area near the spine. These blocks are designed to control pain after breast surgery. During the study, pain will be measured using a scale from 1 to 10 at rest and during movement. Researchers will track the total amount of additional pain medication needed in the first 48 hours after surgery, time to first pain relief, side effects, sleep quality, time to first walking, and overall satisfaction with pain control. Participants will be closely monitored for safety and any complications related to the nerve blocks. The study is conducted at Ain Shams University hospitals and aims to improve pain management for future breast cancer surgery patients.

CONDITIONS

Official Title

Ultrasound-guided Thoracic Interfascial Plane Nerve Block Versus Erector Spinae Plane Block for Pain Control After Modified Radical Mastectomy

Who Can Participate

Age: 21Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Female patients older than 21 years old
  • American Society of Anesthesiologists (ASA) physical status II
Not Eligible

You will not qualify if you...

  • Known allergy to one of the study's medications
  • Skin infections at the site of the needle puncture
  • Significant organ dysfunction including hepatic, renal, or cardiac dysfunction
  • Coagulopathy or recent anticoagulant use
  • Epilepsy
  • Diagnosis of obstructive sleep apnea or pulmonary compromise

AI-Screening

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Trial Site Locations

Total: 1 location

1

Ainshams University Hospitals

Cairo, Abbasiya, Egypt, 1181

Actively Recruiting

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Research Team

S

Safie R Abd El Moneim, Masters

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

Frequently Asked Questions

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Published Research Related To This Trial

Evaluation of postoperative pain in patients undergoing modified radical mastectomy with pectoralis or serratus-intercostal fascial plane blocks.

Ushkiran Kaur, Chetna Shamshery, Anil Agarwal...

https://pubmed.ncbi.nlm.nih.gov/32987492

Refining a great idea: the consolidation of PECS I, PECS II and serratus blocks into a single thoracic fascial plane block, the SAP block-a concern on the muscle pain.

Hongye Zhang, Yongsheng Miao, Zongyang Qu

https://pubmed.ncbi.nlm.nih.gov/31653798
Ultrasound-guided Thoracic Interfascial Plane Block versus Erector Spinae Plane Block for Pain Control After Modified Radical Mastectomy in Patients Undergoing Breast Cancer Surgery | DecenTrialz