Actively Recruiting

Age: 18Years +
FEMALE
NCT05610501

Ultrasound-guided Tru-Cut Biopsy in Pelvic Masses.

Led by Universitaire Ziekenhuizen KU Leuven · Updated on 2024-07-03

200

Participants Needed

4

Research Sites

208 weeks

Total Duration

On this page

Sponsors

U

Universitaire Ziekenhuizen KU Leuven

Lead Sponsor

U

UZ Leuven, Leuven, Belgium

Collaborating Sponsor

AI-Summary

What this Trial Is About

In a transvaginal tru-cut biopsy, guided by ultrasound, a needle is inserted through the vaginal wall into a pelvic lesion and a few pieces of tissue are obtained for examination. This clinical trial is organized to evaluate the safety and efficacy of transvaginal tru-cut biopsy in a large group of patients with tumors in the small pelvis.

CONDITIONS

Official Title

Ultrasound-guided Tru-Cut Biopsy in Pelvic Masses.

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Lesion accessible for biopsy without obstruction by organs or vessels; for transvaginal approach, no severe vaginal narrowing, atrophy, or vaginismus; lesion within needle reach
  • Lesion has a solid component; purely cystic lesions are excluded
  • Patients needing biopsy for participation in clinical trials on gynecological tumors requiring tissue for translational research
  • Patients with suspicious primary disseminated gynecologic tumors unsuitable for primary surgery due to comorbidities or extensive disease
  • Patients with suspicious primary disseminated non-gynecologic tumors requiring histological confirmation
  • Patients with possible recurrence of gynecological tumors needing confirmation before treatment
  • Patients with possible recurrence of non-gynecological tumors needing confirmation before treatment
  • Patients with solitary tumor of unknown type in vaginal wall, parametria, retroperitoneum, or uterine wall suitable for biopsy without risk of abdominal spillage
Not Eligible

You will not qualify if you...

  • Patients younger than 18 years
  • Clotting disorders or anticoagulation therapy that prevent safe biopsy despite adjusted treatment
  • Vaginal or pelvic infections
  • Poor overall health status preventing oncologic treatment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 4 locations

1

UZ Leuven

Leuven, Belgium

Actively Recruiting

2

First Faculty of Medicine, Charles University

Prague, Czechia

Not Yet Recruiting

3

Fondazione Policlinico Universitario A. Gemelli, IRCSS

Rome, Italy

Not Yet Recruiting

4

Department of Clinical Science and Education, Karolinska Institutet and Department of Obstetrics and Gynecology, Södersjukhuset

Stockholm, Sweden

Not Yet Recruiting

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Research Team

W

Wouter Froyman, MD, PHD

CONTACT

S

Stefan Timmerman, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Ultrasound-guided Tru-Cut Biopsy in Pelvic Masses. | DecenTrialz