Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06518785

Ultrasound Neuromodulation of the Brain for Alcohol Use Disorder

Led by University of California, San Francisco · Updated on 2025-09-04

25

Participants Needed

1

Research Sites

294 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to examine the effects of Low-Intensity Focused Ultrasound (LIFU) on brain activity in patients with alcohol use disorder.

CONDITIONS

Official Title

Ultrasound Neuromodulation of the Brain for Alcohol Use Disorder

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female aged 18 years or older
  • Diagnosis of alcohol use disorder based on DSM-5 criteria with at least two symptoms causing significant impairment within the past 12 months
  • Willingness to undergo brain MRI and follow the study protocol
Not Eligible

You will not qualify if you...

  • Pregnant or breastfeeding
  • Any condition or abnormality compromising patient safety or data quality
  • Non-English speaking
  • Currently receiving other investigational treatments for alcohol use disorder
  • Diagnosis of primary psychosis, Bipolar I disorder, or severe personality disorder
  • Active suicidal thoughts or suicide attempt within the last 5 years
  • Cognitive impairment with MoCA score below 24
  • Significant medical or neurological disease or life expectancy under 12 months
  • Significant brain abnormalities on imaging
  • Any contraindications to MRI

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of California, San Francisco

San Francisco, California, United States, 94143

Actively Recruiting

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Research Team

C

Catherine Borror, BS, CCRP

CONTACT

S

Sierra Brandts, BS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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Ultrasound Neuromodulation of the Brain for Alcohol Use Disorder | DecenTrialz