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UmbREALung - A Retrospective and Prospective, Observational, Real World Multi-cohort Study of Patients With Non-small Cell Lung Cancer (NSCLC) Initiating Approved Drugs Developed by AZ or as Part of an AZ Alliance
Led by AstraZeneca · Updated on 2026-03-20
300
Participants Needed
52
Research Sites
393 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is an ambispective, observational, multicenter and multicohort study, targeting patients with NSCLC initiating approved drugs developed by AZ or as part of an AZ alliance, in the participating countries, as monotherapy or in combination at any stage of disease. Three cohorts are designed, based on the stage of NSCLC (resectable, unresectable and metastatic). The multicohort study is modular in design. Specific modules will be set up separately to assess each new indication of drugs developed by AZ or as part of an AZ alliance once European marketing authorization (MA) has been granted and made available in the participating countries. Patients will be enrolled in the study if they have received (retrospective), receive (retrospective and prospective) or will receive (prospective) approved drugs developed by AZ or as part of an AZ alliance according to the eligibility criteria. Treatment plan and decision are made independently by each treating physician prior to inclusion in this study.
CONDITIONS
Official Title
UmbREALung - A Retrospective and Prospective, Observational, Real World Multi-cohort Study of Patients With Non-small Cell Lung Cancer (NSCLC) Initiating Approved Drugs Developed by AZ or as Part of an AZ Alliance
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients (≥ 18 years old)
- Patients with histologically or cytologically proven NSCLC
- Patients initiated with approved drugs developed by AZ or as part of an AZ alliance at the time of the enrollment or within the previous three weeks
- Informed patients who consent to participate in the study as per local regulations
You will not qualify if you...
- Patients participating in an interventional clinical trial for NSCLC, except low-interventional studies where the intervention does not involve NSCLC treatment
- Patients already enrolled in another module of the cohort in UMBREALUNG
- Patients under safeguard of justice, curatorship or guardianship
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 52 locations
1
Research Site
Aix-en-Provence, France, 13100
Actively Recruiting
2
Research Site
Angers, France, 49933
Actively Recruiting
3
Research Site
Aurillac, France, 15000
Actively Recruiting
4
Research Site
Auxerre, France, 89000
Actively Recruiting
5
Research Site
Avignon, France, 84918
Actively Recruiting
6
Research Site
Bezannes, France, 51430
Not Yet Recruiting
7
Research Site
Béziers, France, 34500
Not Yet Recruiting
8
Research Site
Blois, France, 41016
Actively Recruiting
9
Research Site
Bordeaux, France, 33000
Actively Recruiting
10
Research Site
Bourg-en-Bresse, France, 01012
Actively Recruiting
11
Research Site
Caen, France, 14052
Not Yet Recruiting
12
Research Site
Carcassonne, France, 11010
Actively Recruiting
13
Research Site
Chalon Sur Sa Ne, France, 71321
Actively Recruiting
14
Research Site
Chambéry, France, 73000
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15
Research Site
Châteauroux, France, 36019
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16
Research Site
Créteil, France, 94000
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17
Research Site
Dieppe, France, 76202
Actively Recruiting
18
Research Site
Dinan, France, 22100
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19
Research Site
Dreux, France, 28102
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20
Research Site
Epagny METZ Tessy, France, 74370
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21
Research Site
Fort de France Cedex, France, 97200
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22
Research Site
Le Coudray, France, 28630
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23
Research Site
Limoges, France, 87000
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24
Research Site
Lyon, France, 69437
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25
Research Site
Marseille, France, 13003
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26
Research Site
Marseille, France, 13285
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27
Research Site
Marseille, France, 13915
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28
Research Site
Meaux, France, 77100
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29
Research Site
Metz, France, 57000
Not Yet Recruiting
30
Research Site
Metz, France, 57070
Actively Recruiting
31
Research Site
Mulhouse, France, 68100
Actively Recruiting
32
Research Site
N MES, France, 30029
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33
Research Site
Nancy, France, 54100
Actively Recruiting
34
Research Site
Nantes, France, 44200
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35
Research Site
Neuilly-sur-Seine, France, 92200
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36
Research Site
Nice, France, 06000
Actively Recruiting
37
Research Site
Perpignan, France, 66000
Actively Recruiting
38
Research Site
Reims, France, 51726
Not Yet Recruiting
39
Research Site
Rouen, France, 76000
Not Yet Recruiting
40
Research Site
Saint-Brieuc, France, 22000
Actively Recruiting
41
Research Site
Saint-Etienne, France, 42100
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42
Research Site
Saint-Herblain, France, 44800
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43
Research Site
Saint-Priest-en-Jarez, France, 42271
Not Yet Recruiting
44
Research Site
Strasbourg, France, 67000
Actively Recruiting
45
Research Site
Suresnes, France, 92151
Actively Recruiting
46
Research Site
Toulouse, France, 31076
Actively Recruiting
47
Research Site
Troyes, France, 10000
Not Yet Recruiting
48
Research Site
Valenciennes, France, 59300
Actively Recruiting
49
Research Site
Vandœuvre-lès-Nancy, France, 54519
Not Yet Recruiting
50
Research Site
Vannes, France, 56017
Actively Recruiting
51
Research Site
Villefranche-sur-Saône, France, 69655
Actively Recruiting
52
Research Site
Villeurbanne, France, 69100
Actively Recruiting
Research Team
A
AstraZeneca Clinical Study Information Center
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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