Actively Recruiting

Age: 18Years +
FEMALE
Healthy Volunteers
NCT06042803

UmbrelLACT Study: Clinical Lactation Study on the Exposure to Medicines Via Human Milk

Led by Universitaire Ziekenhuizen KU Leuven · Updated on 2025-02-27

30

Participants Needed

1

Research Sites

208 weeks

Total Duration

On this page

Sponsors

U

Universitaire Ziekenhuizen KU Leuven

Lead Sponsor

I

Innovative Medicines Initiative

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this observational study is to determine the concentration of medicines in human milk during maternal medicine intake. The main questions it aims to answer are: * What is the concentration of maternal medicines in human milk? * What is the (estimated) intake and exposure in the breastfed infant? Participants will be asked to * fill out a questionnaire regarding medical data of the mother and child * track medication intake for 3 days * collect milk samples during 24 hours * optionally, donate 2 blood samples of the mother and give consent to one blood sample of the child * fill out a questionnaire regarding the general health of the child.

CONDITIONS

Official Title

UmbrelLACT Study: Clinical Lactation Study on the Exposure to Medicines Via Human Milk

Who Can Participate

Age: 18Years +
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Breastfeeding women aged 18 years or older
  • Currently exclusively or partially breastfeeding or expressing milk at the time of milk sampling
  • Using medicines for any reason, with at least five half-lives of the medicine taken
  • Willing to express and collect human milk
  • Signed informed consent to participate and for processing personal data
  • Infants born at 24 weeks gestation or later
  • Parental signed informed consent for infant participation and data processing
Not Eligible

You will not qualify if you...

  • Maternal age under 18 years
  • Mother of twins
  • Not meeting the inclusion criteria

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Universitaire Ziekenhuizen KU Leuven

Leuven, Vlaams-Brabant, Belgium, 3000

Actively Recruiting

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Research Team

A

Anne Smits, MD, PhD

CONTACT

M

Martje Van Neste, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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